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Scientists hunt for molecules that predict spinal cord healing

NCT ID NCT07383077

Knowledge-focused Sponsor: Prof. Sandra Vieira Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study analyzed blood and other samples from 106 adults with recent spinal cord injuries to find molecules linked to better recovery. Researchers measured changes in these molecules before and after rehabilitation and one year after injury. The goal is to identify biological clues that could lead to new treatments for spinal cord injury.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could identify biological markers that help predict recovery after spinal cord injury, potentially pointing toward new drug targets.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear biomarkers, and any identified candidates would need years of further testing before becoming therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

106 people

The number who actually took part.

Started

May 2021

Finished

Oct 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients admitted to the North Rehabilitation Center ("Centro de Reabilitação do Norte, CRN-ULSGE") between 1st of May 2021 and 16th of October 2023, following a traumatic spinal cord injury.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinically diagnosed with traumatic spinal cord injury * Adults (≥18 years). * Injury occurred less than 6 months ago (subacute phase). * Classification A-D in The American Spinal Injury Association (ASIA) Impairment Scale (AIS). * Any neurological level of injury. Exclusion Criteria: * Use of probiotics one-month prior admission. * Use of immunomodulatory drugs one-month prior admission. * Major gastrointestinal surgery in the last five years. * Active gastrointestinal diseases. * Other CNS diseases (besides SCI).

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spinal cord injury

Contacts and locations

Locations

  • Centro de Reabilitação do Norte (CRN) / Unidade Local de Saúde Gaia e Espinho, E.P.E. (ULSGE), Vila Nova de Gaia,, Portugal

    Vila Nova de Gaia, 4405-565 Vila Nova de Gaia, Portugal

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