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Warm blankets may cut heart risk for paralyzed patients

NCT ID NCT04971408

Disease control Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

People with spinal cord injury (SCI) face higher risks of heart disease and diabetes, partly due to chronic inflammation and poor blood vessel function. Exercise helps but is often not possible. This small study tested whether repeated passive heating (using a water-perfused suit or electric blanket) three times a week for eight weeks could lower inflammation and improve metabolism and blood vessel health in 10 adults with stable SCI. The goal was to see if this simple, accessible method could reduce key risk factors for heart disease and diabetes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
passive heat stress (water perfused suit or electrical heating blanket)
What this could lead to
If it works, this could offer a simple, accessible way to lower heart disease and diabetes risk in people with spinal cord injury who cannot exercise.
What could go wrong
This is a very small, early study (10 participants) with no control group for comparison. The benefits seen may not be large or lasting, and longer-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

10 people

The number who actually took part.

Started

Jul 2022

Finished

Jun 2024

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Stable SCI over 1 year of duration Exclusion Criteria: * Persons who smoke cigarettes * Daily administration of anti-inflammatory medications * Daily administration of vasoactive medications * Pressure ulcer stage 3 or 4 * History of heat related illness

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Conditions

The condition(s) this trial relates to.

glucose metabolism disease spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic inflammation Endothelial function Glucose metabolism Spinal cord injury

Contacts and locations

Locations

  • South Texas Health Care System, San Antonio, TX

    San Antonio, Texas, 78229-4404, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.