POSTOPERATIVE COMPLICATIONS

This study tests whether using a reinforcement patch on the stapler during stomach cancer surgery can reduce complications like leaks. About 382 adults with gastric cancer will be randomly assigned to get either the patch or a standard stapler. The main goal is to see if the patc…

This study compares two types of stitches used to close the top of the vagina after a hysterectomy (removal of the uterus) for gynecologic cancers. The goal is to see if a newer double-layer self-locking stitch reduces complications like infection, bleeding, or reopening of the i…

This study tests whether adding a concentrated form of albumin (a protein) to standard IV fluids during a major surgery for abdominal cancer can reduce complications after the operation. About 140 adults with cancer that has spread to the lining of the abdomen will be randomly as…

This study is testing a new surgical stapler (Signia circular stapler) in about 137 people having elective left-sided colon, sigmoid, or rectal surgery. The main goal is to see how often a serious complication called anastomotic leak (a leak where the bowel is reconnected) happen…

This study tests a new, dye-free way to check blood flow during gastrointestinal surgery. About 200 adults having planned gut surgery will be randomly assigned to either the new light-based method (iPPG) or the standard dye method (ICG). The goal is to see if the new method works…

This study tests whether a remote expert can guide a bedside ultrasound to accurately detect fluid buildup in the belly after liver surgery. About 40 patients will be scanned within 72 hours of surgery. The goal is to see if this remote method works as well as a standard ultrasou…

This study looks at whether playful breathing exercises, like blowing balls or bubbles, can lower anxiety before surgery and reduce confusion after waking up in children aged 3 to 7. About 80 kids having planned surgery will be observed. Researchers will measure anxiety using a s…

This study compares four mouthwashes (Bone Bioactive Liquid, Hyaluronic Acid, Chlorhexidine, and Warm Saline) to see which one helps the healing of wisdom tooth extraction sockets. One hundred adults who need a lower wisdom tooth removed will be randomly assigned to use one of th…

This study tests whether tea tree oil mouthwash works as well as chlorhexidine mouthwash for reducing pain, swelling, and jaw stiffness after having a wisdom tooth removed. About 54 adults will use one of the two mouthwashes three times a day for a week. Researchers will measure …

This study looks at three different breathing treatments (IPPB, EzPAP, and Metaneb) to see which one helps the lungs expand and recover best after heart surgery. About 324 adults who had certain types of heart surgery will take part. The goal is to find out which therapy improves…

This study tests whether a smartphone app that tracks symptoms and gives feedback can help lung cancer patients do their prescribed rehab exercises after minimally invasive surgery. About 736 adults aged 18-75 will use the app for one month after leaving the hospital. The goal is…

This study tests whether a special nurse-led education session and a direct referral to pelvic floor physiotherapy before prostate cancer surgery can reduce urine leakage afterward. About 80 men having prostate removal at Beaumont Hospital will be randomly assigned to either stan…

This study tests whether having family members involved in a child's anesthesia care can lower the chance of emergency delirium—a state of confusion and agitation—after surgery. The trial will include 444 children aged 2 to 6 years having short elective surgeries. Researchers wil…

This study tests whether helping people sleep better for 4 weeks before knee or hip replacement surgery can reduce pain and speed recovery afterward. About 100 adults with insomnia and osteoarthritis will receive either a brief sleep therapy (CBT-I) or sleep education before thei…

This study compares two ways to deliver breathing exercises before and after lung cancer surgery: in-person sessions with a physiotherapist versus using a smartphone app (Fissios App) alongside those sessions. The goal is to see if the app helps reduce complications like infectio…

This study will use artificial intelligence to predict complications in children who have a common heart defect repaired with a catheter-based procedure. Researchers will analyze data from over 5,000 patients, including lab results, images, and health records, to build a model th…

This study looks at whether a special nutrition shake given after surgery can help older adults (70+) regain their physical and mental abilities faster. Half of the 100 participants will receive the shake daily for 30 days, while the other half gets standard recovery advice. The …

This study is testing a new AI tool called DeepComp that uses CT scans and patient data to predict which stomach cancer patients are at high risk for serious complications after surgery. Researchers will enroll 500 patients across five medical centers and compare the AI's predict…

This study looks at 500 adults having cancer surgery to see which risk score best predicts if they'll need intensive care afterward. Doctors will compare several scoring tools to find the most accurate one. The goal is to help plan better care and use hospital resources wisely.

This study follows 42 adults admitted to the intensive care unit after surgery. Researchers measure inflammation markers in the blood to see if they can predict serious complications or death. The goal is to better understand which patients are at highest risk, not to test a new …

This study watches 1,200 older adults (65+) before, during, and after surgery to learn why some get complications like delirium (sudden confusion). Researchers collect blood samples and health info to build a risk prediction model. The goal is to better understand and eventually …

This study reviews 600 patients' records over 10 years to find out why some people develop low calcium levels after thyroid removal. Low calcium is a common complication, affecting up to half of patients. The goal is to identify risk factors so doctors can better predict, prevent…

This study is collecting blood samples from 5000 people having heart, colorectal, vascular, or lung surgery to find biological markers that can predict serious complications like infections, kidney injury, or death within 30 days. The goal is to improve risk assessment and guide …

This study looks back at the medical records of 350 adults in France who had surgery for esophageal cancer between 2017 and 2024. The goal is to understand how often infections like pneumonia happen after this surgery, what factors increase the risk, and how these infections affe…

This study is looking for ways to predict postoperative delirium—a state of confusion that can happen after surgery—in patients aged 65 and older. Researchers will measure certain substances in the blood before and after surgery to see if they can identify who is at risk. The goa…

This study looks at 1,800 adults having major liver surgery to create a tool that predicts heart injury after the operation. Researchers will check heart enzyme levels and use patient details and surgical methods to build the model. The goal is to help doctors identify high-risk …

This study tests a new way to give fluids during abdominal surgery. Doctors will use breathing-related changes in the internal jugular vein (a neck vein) to guide how much fluid to give. The goal is to see if this approach reduces complications like infections, heart issues, or k…

This study will see if an artificial intelligence (AI) model can predict serious heart problems within 30 days after gastrointestinal surgery better than current risk scores. Researchers will review medical records from 5000 adults having surgery at Bach Mai Hospital. The AI mode…

This study looks at whether checking dental patients for undiagnosed sleep apnea before surgery under anesthesia can help predict and prevent breathing problems after the procedure. Researchers will screen 240 adults using standard questionnaires and refer high-risk patients for …

This study looks at whether a blood test called phosphatidylethanol (PEth), which shows how much alcohol someone has had over the past few weeks, can predict problems after surgery. Researchers will test 170 adults who drink alcohol and are having surgery at University Hospitals …

This study is a large registry that will collect information from 8,000 people having heart or chest surgery. The goal is to find out which factors before and during surgery are linked to serious problems after surgery, such as death, shock, or needing another operation. By under…

This study looks at whether taking out the breathing tube after robotic surgery in the recovery room instead of the operating room can save time. About 218 adults having robotic surgery will be randomly assigned to have their tube removed in the OR or the recovery room. The goal …

This study looks at whether adjusting the breathing machine based on real-time lung stiffness during back surgery can help patients breathe better afterward. About 71 adults having lumbar spine surgery will be randomly assigned to either standard ventilation or a personalized met…

This study compares two types of staplers (linear vs circular) used to reconnect the esophagus to the small intestine after complete stomach removal in gastric cancer patients. Researchers will track complications and surgery time in 100 participants to see which stapler works be…

This study looks at whether showering with surgical drains in place after breast reduction or tummy tuck surgery increases the chance of infection or other complications. About 100 adults will be randomly assigned to either shower or not shower while they have drains. The goal is…

This study looks at whether a special heart ultrasound done before cardiovascular surgery can help predict which patients will develop atrial fibrillation (an irregular heartbeat) after their operation. Researchers will follow 138 adults who are in normal rhythm before surgery an…

This study follows 30 women aged 18-70 who are having DIEP flap breast reconstruction after breast cancer surgery. Researchers will take blood samples before and after surgery to measure markers of inflammation and stress. The goal is to learn more about how the body heals and to…