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Can a warmer, wetter breath during surgery protect the lungs?

NCT ID NCT07729319

Knowledge-focused Sponsor: Marmara University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

General anesthesia bypasses the nose's natural warming and moistening of air, letting cold, dry gases reach the lungs. This study compares two humidification methods—active heated humidification versus a passive heat-moisture exchanger—in adults undergoing video-assisted thoracoscopic surgery (VATS) with one-lung ventilation. Researchers will track lung complications within the first week after surgery to see whether either approach is linked to fewer problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
active heated humidification or passive heat-moisture exchanger device used during anesthesia
What this could lead to
If one method proves better, it could point toward a simple change in anesthesia practice that reduces lung complications after chest surgery.
What could go wrong
This is an observational study, not a randomized trial, so results may be influenced by factors other than the humidification method. The devices are chosen by the anesthesiologist, not assigned by the study.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients undergoing elective video-assisted thoracoscopic lung resection requiring one-lung ventilation at Marmara University Pendik Training and Research Hospital.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 to 75 years * Elective video-assisted thoracoscopic surgery (VATS) * Lung resection requiring general anesthesia * Planned one-lung ventilation * Written informed consent Exclusion Criteria: * Emergency surgery * Pregnancy * Preoperative mechanical ventilation * Previous enrollment * Refusal to participate

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Conditions

The condition(s) this trial relates to.

Postoperative Complications ventilation pneumonitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Air conditioning Humidification Postoperative complications Pulmonary complications in surgical patients Video assisted thoracic surgery (VATS)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Marmara University

    RECRUITING

    Istanbul, Istanbul, 34722, Turkey (Türkiye)

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