Can a simple blood test forecast surgery dangers?
NCT ID NCT05199025
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find out if certain substances in the blood can help predict serious complications after high-risk surgeries like heart, lung, or colon operations. Researchers will collect blood samples from about 5,000 patients before and after surgery and track their recovery for 30 days. The goal is to create a tool that helps doctors identify patients at higher risk and improve their care. There is no direct treatment or benefit for participants, but the information gathered may help future patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2021
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of patients undergoing surgery in the St. Antonius Hospital and the Amphia hospital.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Cardiac surgery (isolated coronary artery bypass grafting or combined with single valve surgery, isolated single valve surgery) * Gastrointestinal surgery (colorectal, pancreatic, gastric surgery). * Vascular surgery (open and endovascular aortic surgery, peripheral vascular surgery) * Lung surgery (pneumonectomy,(bi)(sleeve)lobectomy or segmentectomy) Exclusion Criteria: * Age \< 18 years * Pregnancy * Emergent surgery * No informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Amphia Hospital
RECRUITINGBreda, North Brabant, 4818CK, Netherlands
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St Antonius Hospital
RECRUITINGNieuwegein, Utrecht, 3430 EM, Netherlands
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