Blood test may reveal hidden surgery risks in drinkers
NCT ID NCT06864819
First seen Jun 27, 2026 · Last updated Sep 04, 2026 · Updated 1 time
Summary
This study looks at whether a blood marker called phosphatidylethanol (PEth), which reflects alcohol use over the past few weeks, can predict complications after surgery. Researchers will test PEth levels in 170 adults having elective surgery at University Hospitals Cleveland Medical Center who are expected to stay in the hospital for at least three days. The goal is to see if higher PEth levels are linked to problems like confusion, lung or heart issues, infections, or longer hospital stays.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors identify patients at higher risk for post-surgery problems based on their alcohol use, leading to better care.
- What could go wrong
- This is an observational study, not a treatment trial. It may find no clear link between PEth levels and outcomes, or the results may not apply to all surgery patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 170 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
May 2025
- Expected to finish
-
Nov 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients undergoing elective surgery at UHCMC.
- Ages
-
21 to 79 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 1\. Age range: 21-79 * 2\. Patients undergoing elective surgery at UHCMC with planned ICU admission * 3\. Patients undergoing elective surgery at UHCMC with expected in-hospital admission for three or more days * 4\. Only patients who consume alcoholic beverages on a regular basis. Exclusion Criteria: * 1\. Patients undergoing same day outpatient surgeries or expected to be admitted less than three days post-operatively * 2\. Subjects who have received a blood transfusion within the past month before surgery * 3\. Pregnant subjects
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Alcohol use disorder are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
University Hospital
RECRUITINGCleveland, Ohio, 44106, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Brain-Training games rewire the mind to fight alcohol addiction?
- Can a Stress-Hormone blocker take the edge off alcohol?
- A standard IV fluid dose may reveal who is at risk after bowel surgery
- Can MDMA plus therapy help veterans fight both PTSD and alcohol addiction?
- Brain scans probe opioid receptor imbalance in alcohol use disorder
- Spinal taps open a window on alcohol use disorder