POSTOPERATIVE COMPLICATIONS

This study compares using a reinforcement patch on surgical staplers versus standard staplers during stomach surgery (gastrojejunostomy) for gastric cancer. The goal is to see if the patch lowers the risk of leaks, bleeding, or narrowing at the connection site. About 382 patients…

This study tests whether applying a cold plasma (non-thermal plasma) to the surgical site during standard drainage of a chronic subdural hematoma can lower the chance of the blood clot returning within 6 months. Forty adults needing surgery for this condition will be randomly ass…

This study tests whether adding a protein called albumin to standard IV fluids during a major cancer surgery (cytoreduction with heated chemotherapy) can reduce complications. The surgery causes large fluid shifts, and the trial aims to see if albumin helps patients recover bette…

This study is testing a new surgical stapler, called the Signia circular stapler, in people having left-sided colon, sigmoid, or rectal surgery. The goal is to see if it lowers the chance of a leak where the colon is reconnected. About 137 adults will take part, and the main focu…

This study looks at whether giving patients with bone or soft tissue sarcoma a special nutritional supplement twice daily before surgery can reduce complications and help maintain muscle mass. About 100 adults scheduled for tumor removal will be randomly assigned to receive eithe…

This study compares two types of stitches used to close the vaginal cuff after laparoscopic hysterectomy in women with gynecologic cancers. The goal is to see if a newer self-locking stitch reduces complications like wound opening, infection, or bleeding within three months after…

This study tests a new, dye-free way to see blood flow during surgery for stomach or colon cancer. About 200 adults having gut surgery will be randomly assigned to get either the new light-based method (iPPG) or the standard dye method (ICG). The goal is to see if the new method …

This study looks at whether a remote expert can guide a bedside ultrasound to find fluid buildup in the belly after liver surgery. About 40 patients will be scanned within 72 hours of their operation. The goal is to see if this remote method is as accurate as a standard ultrasoun…

This study tests whether playful breathing exercises—like blowing bubbles or cotton balls—can lower anxiety before surgery and reduce confusion after waking up in children aged 3 to 7. About 80 kids will practice these games at home 2-3 days before their operation. Researchers wi…

This study compares four different mouthwashes—Bone Bioactive Liquid, Hyaluronic Acid, Chlorhexidine, and Warm Saline—to see which one helps the healing of tooth sockets after wisdom tooth removal. About 100 adults will be randomly assigned to use one of the rinses. The goal is t…

This study compares two ways of doing breathing exercises before and after lung cancer surgery: in-person sessions with a physiotherapist versus using a smartphone app (Fissios App) alongside those sessions. The goal is to see if the app helps reduce complications like infections…

This trial tests whether a structured nurse-led education session before prostate cancer surgery, plus a direct referral to pelvic floor physiotherapy, can reduce urine leakage afterward. Eighty men scheduled for prostate removal will be randomly assigned to either standard care …

This study tests whether tea tree oil mouthwash can reduce pain, swelling, and jaw stiffness after wisdom tooth removal as well as the standard chlorhexidine mouthwash. Fifty-four adults getting their lower wisdom teeth out will use one of the two mouthwashes three times daily fo…

This study tests whether a smartphone app that tracks symptoms and gives feedback can help lung cancer patients do their prescribed rehab exercises after minimally invasive surgery. About 736 patients will use the app and be split into two groups: one gets extra support from thei…

This study tests whether helping people sleep better for four weeks before knee or hip replacement surgery can reduce pain and speed up recovery afterward. One hundred adults with insomnia symptoms will receive either a brief sleep therapy or sleep education before their operatio…

This study tests whether a special vacuum bandage (negative pressure wound therapy) can prevent infections better than standard dressings after skin grafts on the lower leg. About 242 adults who have a skin tumor removed and need a skin graft will take part. The bandage is applie…

This study tests a simple idea: having a parent or family member involved in a child's anesthesia care to reduce emergency delirium—a state of confusion, crying, or thrashing when waking up from surgery. Researchers will compare this family-centered approach to standard care in 4…

This study compares three breathing treatments (IPPB, EzPAP, and Metaneb) to see which one helps lungs expand and recover best after heart surgery. About 324 adults who had coronary bypass or valve surgery will take part. The goal is to find the most effective therapy to improve …

This registry is collecting information from 8,000 people undergoing heart or chest surgery. The goal is to see how factors before and during surgery relate to serious complications like death, shock, or infection. By analyzing this data, researchers hope to find ways to improve …

This study is testing whether a special heart ultrasound can predict who will develop atrial fibrillation after heart surgery. Researchers will measure how well the heart's upper chambers work together before surgery in 138 patients. They will then track patients during recovery …

This study is creating a prediction tool to estimate the risk of heart injury after major liver surgery. Researchers will collect data from 1,800 patients undergoing liver surgery, including their health history, surgical details, and blood tests. The goal is to develop a model t…

This study tests whether moving patients to the recovery room before removing their breathing tube frees up the operating room faster after robot-assisted surgery. Researchers will compare two approaches in 218 adults: removing the tube in the operating room versus in the post-an…

This study is observing 42 adults who are admitted to the intensive care unit after surgery. Researchers want to see if levels of a substance called IL-6 and other inflammation scores in the blood can help predict which patients are at higher risk of dying or having serious compl…

This study aims to create an artificial intelligence (AI) model that can predict complications in children who have a common heart defect (a hole in the heart wall) repaired with a catheter-based procedure. Researchers will analyze medical records from over 5,000 children, includ…

This study looks at infections that happen after surgery to remove esophageal cancer. Researchers will review medical records of 350 patients who had this surgery in France between 2017 and 2024. The goal is to find out what factors increase infection risk and how infections affe…

This study is looking for ways to predict postoperative delirium—a sudden confusion that can happen after surgery in older patients. Researchers will measure certain substances in the blood of 1,170 patients aged 65 and older before and after major surgery. They hope to find a re…

This study looks at whether a blood marker called phosphatidylethanol (PEth), which reflects alcohol use over the past few weeks, can predict complications after surgery. Researchers will test PEth levels in 170 adults having elective surgery at University Hospitals Cleveland Med…

This study looks at whether showering after surgery while drains are still in place increases the risk of infections or other complications. It will include 100 people having breast reductions or tummy tuck procedures. Half will be told they can shower, and half will be told to w…

This study is testing a new AI tool called DeepComp that uses CT scans to predict which stomach cancer patients are at high risk for serious complications after surgery. Researchers will enroll 500 patients across five hospitals and compare the AI's predictions to what actually h…

This study looks at adults having dental procedures under general anesthesia to see if undiagnosed sleep apnea raises the risk of breathing problems after surgery. Researchers will use two common screening tools (STOP-BANG and ASA criteria) to identify high-risk patients and refe…

This study is testing whether a special nutrition shake given after surgery can help older adults (70+) regain physical and mental function faster. Half of the 100 participants will receive the shake daily for 30 days, while the other half will follow standard recovery advice. Th…

This study reviews 10 years of medical records from 600 adults who had thyroid surgery at Minia University Hospital. The goal is to find out which patients are most likely to develop low calcium levels after surgery, a common complication. By identifying key risk factors, doctors…

This study looks at different scoring systems to see which best predicts whether a person will need intensive care after cancer surgery. Researchers will follow 500 adults having cancer surgery and compare the accuracy of these tools. The goal is to help doctors plan better and u…

This study follows 30 women having DIEP flap breast reconstruction after mastectomy. Researchers will measure inflammation and stress markers in blood samples taken before and after surgery. The goal is to learn how the body heals and what affects recovery, which may help improve…

This study tests a new way to give fluids during abdominal surgery. Doctors will use breathing-related changes in a neck vein to decide how much fluid to give. The goal is to see if this method reduces complications like infections, heart issues, or kidney problems after surgery.…

This study is watching 1,200 older adults (65+) before, during, and after surgery to learn why some get complications like confusion (delirium). Researchers will collect blood samples and health information to build a tool that predicts these risks. The goal is to better understa…

This study compares two types of staplers (linear vs circular) used to reconnect the esophagus to the small intestine after stomach removal surgery for gastric cancer. Researchers want to see which stapler leads to fewer complications and shorter surgery time. About 100 adults wi…

This study aims to find out if certain substances in the blood can help predict serious complications after high-risk surgeries like heart, lung, or colon operations. Researchers will collect blood samples from about 5,000 patients before and after surgery and track their recover…

This study observes 10,000 adults worldwide who need a breathing machine during surgery. Researchers will track lung problems after surgery and how the machine is used. The goal is to find ways to make surgery safer for everyone.

This study will see if an artificial intelligence (AI) model can predict major heart problems within 30 days after gastrointestinal surgery better than current risk scores. Researchers will review medical records of 5,000 adults having surgery at Bach Mai Hospital in 2025-2026. T…