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Could a simple protein improve recovery from aggressive cancer surgery?

NCT ID NCT06351475

First seen Jan 04, 2026 · Last updated Jun 20, 2026 · Updated 27 times

Summary

This study tests whether adding a protein called albumin to standard IV fluids during a major cancer surgery (cytoreduction with heated chemotherapy) can reduce complications. The surgery causes large fluid shifts, and the trial aims to see if albumin helps patients recover better. 140 adults with peritoneal cancer are being randomly assigned to receive either standard fluids or standard fluids plus albumin.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gustave Roussy Institute

    RECRUITING

    Villejuif, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Hautepierre / UIC ARMO

    RECRUITING

    Strasbourg, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut régional du Cancer de Montpellier

    RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • La Pitié Salpetriere hospital

    RECRUITING

    Paris, 75013, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lariboisière hospital

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Robert Debré hospital

    RECRUITING

    Reims, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Saint Louis hospital

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

20% human albumin combined with Ringer's lactate solution

What this could lead to

If it works, this could lead to a standard fluid therapy that reduces serious complications after major abdominal cancer surgery.

What could go wrong

This is a relatively small, early-stage trial (140 patients) and the benefit of albumin in surgery is unproven. There is also a risk of allergic reactions or fluid overload with albumin.

Conditions

The condition(s) this trial relates to.

peritoneal neoplasm Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.