Can we predict the painful cords that follow breast cancer surgery?
NCT ID NCT07780240
First seen Aug 21, 2026 · Last updated Aug 21, 2026
Summary
This study follows women undergoing breast cancer surgery to see how often they develop axillary web syndrome (AWS), also known as cording—tight, painful cords under the arm that can limit movement. Researchers will examine participants before surgery and at several points over six months, checking for cords, measuring shoulder mobility, pain, and arm swelling. The goal is to identify risk factors and timing of AWS, so that rehabilitation can start earlier for those most likely to be affected.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Axillary surgery (sentinel lymph node biopsy or axillary lymph node dissection)
- What this could lead to
- If successful, this could help identify which patients are more likely to develop cording after breast cancer surgery, allowing earlier rehabilitation and better arm function.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. Results may not apply to all patients, and the condition's variability could make findings less definitive.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 250 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Consecutive patients undergoing surgery for breast cancer with axillary staging by sentinel lymph node biopsy or axillary lymph node dissection at the general surgery departments of the two participating centers. Patients who develop axillary web syndrome and those who do not are compared within the same cohort; no separate control group is enrolled.
- Ages
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18 to 80 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Diagnosis of breast cancer with planned surgical treatment * Axillary staging performed by sentinel lymph node biopsy or axillary lymph node dissection * Written informed consent provided Exclusion Criteria: * Preoperative restriction of shoulder range of motion * History of neuromuscular disease affecting the upper extremity * Metastatic disease * Anticipated inability to comply with the follow-up protocol
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Antalya City Hospital
RECRUITINGAntalya, Kepez, 07080, Turkey (Türkiye)
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Bagcilar Training and Research Hospital
RECRUITINGIstanbul, BAGCILAR, 34100, Turkey (Türkiye)
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