PAIN, POSTOPERATIVE

This study compares three different medicaments—including nano-based ones—for treating infected baby molars in children aged 4 to 8. The goal is to see which works best to relieve pain, reduce swelling, and stop infection, both in the clinic and in the lab. The research involves …

This study aimed to see if a short course of steroids (methylprednisolone) after knee replacement surgery could improve pain, movement, and sleep while reducing the need for strong painkillers. It was designed for adults having their first knee replacement, but the study was with…

This study tests if a new 3-point stitch method for holding mesh in place during hernia repair leads to less pain and fewer problems than the usual method. About 64 adults having hernia surgery will take part. The goal is to see which approach helps people heal better after surge…

This study looks at whether playing music before or during hernia repair surgery can help lower pain after the operation. About 308 adults having surgery at Bethesda Surgery Center will take part. Researchers will measure pain scores and how much narcotic pain medicine is needed …

This study planned to test whether adding ear acupuncture during surgery to repair a broken lower leg could help patients use fewer opioid painkillers afterward. It was designed for adults aged 18–64 having ankle or foot fracture surgery. However, the study was withdrawn before e…

This study looks at whether giving fewer opioid pain pills after laparoscopic hysterectomy still keeps pain under control. About 120 adults having this surgery for non-cancer reasons will be randomly assigned to get either a standard or a reduced opioid prescription. The goal is …

This study tests whether repeated magnetic pulses to the brain (rTMS) can reduce chronic nerve pain that hasn't responded to other treatments. About 32 adults with conditions like post-stroke pain or nerve injury will receive rTMS daily for two weeks. The goal is to see if this n…

This study tests a new pain medicine called NTM-001 for people with moderate to severe pain after bunion surgery. About 341 adults aged 18 to 64 will receive either NTM-001, a placebo, or IV morphine to compare how well it relieves pain over 24 hours. The goal is to see if NTM-00…

This study planned to test whether giving ear acupuncture during wrist surgery could lower the amount of opioid painkillers patients need afterward. It was designed for adults aged 18-64 having a specific type of wrist fracture repair. However, the study was withdrawn before any …

This pilot study is testing whether a daily 20-minute meditation practice, done for 2-4 weeks before and 2 weeks after kidney stone surgery, can reduce pain and anxiety in patients aged 12 and older. Half of the 50 participants will learn meditation, while the other half will rec…

This study compares two types of nerve blocks (serratus plane block and rhomboid intercostal plane block) to see which provides better pain relief after breast reduction surgery. 90 women will receive one of the blocks before surgery, and their pain levels and need for opioid pai…

This study compares a standard painkiller (bupivacaine) with a slow-release version (Exparel) to control pain after eye removal surgery. About 88 adults having their eye removed will be randomly assigned to receive one of the two painkillers during surgery. The goal is to see if …

This study tests a Pain and Coordination Plan (PAC-plan) for people who have had accidental injuries and are taking opioids after surgery. The plan includes guidance on stopping opioids, a follow-up doctor visit, and better teamwork between hospital and primary care. Researchers …

This study aimed to see if a special nerve block (parasternal subpectoral plane block) could lower pain and the need for strong painkillers after open-heart surgery. It planned to compare the nerve block using a numbing medicine (bupivacaine) versus a placebo (salt water) in adul…

This study tests whether giving magnesium through an IV during hip surgery can lower pain and the need for strong painkillers afterward. About 50 adults having a specific hip procedure (periacetabular osteotomy) are taking part. Researchers will measure pain levels and medication…

This study looks at three ways to manage pain after surgery for pectus excavatum, a chest wall deformity often fixed in teenagers. The goal is to find which method works best to reduce pain and the need for strong painkillers. About 158 patients aged 12 to 21 will be randomly ass…

This study tests whether a nerve block given before heart surgery can help manage pain and reduce the need for strong painkillers like opioids. About 150 adults having certain heart surgeries will be randomly assigned to receive one of two types of numbing medicine. The goal is t…

This study tests whether a specific nerve block (erector spinae plane block) can reduce the amount of morphine needed for pain after minimally invasive spinal fracture surgery. About 86 adults will be randomly assigned to receive either the nerve block or a placebo. The main goal…

This study tests whether watching immersive 360-degree videos through a VR headset can reduce pain, anxiety, and the need for strong painkillers during dressing changes after burn surgery. About 80 adults who had skin grafts will try the VR distraction tool. The goal is to find a…

This study looks at whether adding a mild electrical stimulation device (like a TENS unit) to standard pain management can reduce pain and improve quality of life for 90 people recovering from lung cancer surgery. The treatment is non-invasive and aims to lower inflammation and r…

This study tests a pain control method called intercostal nerve cryotherapy for people having minimally invasive lung surgery. The treatment freezes nerves between the ribs to block pain signals. Researchers will compare pain levels and morphine use between patients who receive c…

This study was designed to see which of two nerve blocks works better for pain relief after hip surgery in teens and young adults. It was withdrawn before any participants were enrolled, so no results are available. The goal was to compare a quadratus lumborum block with an erect…