PAIN, POSTOPERATIVE

This study compares two types of nerve blocks for pain control after hip surgery: the newer PENG block and the standard femoral nerve block. Researchers will measure pain levels and leg muscle strength in 100 adults aged 40 and older. The goal is to see which method provides bett…

This study tests whether giving a single dose of methadone during spine surgery can improve pain control and reduce the need for other opioids. About 30 adults having elective spine surgery will be randomly assigned to receive either standard pain medicines or a single dose of me…

This study tests whether an eye drop called BL1332 can reduce pain after PRK, a type of laser eye surgery. About 123 adults aged 18 to 58 who are scheduled for PRK will receive either the study drop or a placebo. The main goal is to see if the drop lowers pain scores in the first…

This study tests whether a new form of the anti-inflammatory drug dexamethasone (dexamethasone palmitate) can better prevent moderate-to-severe pain after surgery compared to the standard version. About 446 adults having various surgeries will receive the drug before their operat…

This study compares a new pain medicine called tegileridine to morphine for pain relief after abdominal surgery. The goal is to see if tegileridine helps the bowels start working again faster within 72 hours after surgery. About 152 adults having planned abdominal surgery will be…

This study looks at whether a single-shot nerve block (using the drug ropivacaine) can reduce pain and the need for strong painkillers in children and teens after ACL knee surgery. About 160 participants aged 13 and older will be randomly assigned to get the nerve block during su…

This study tests whether adding high-intensity laser therapy to standard physical therapy helps reduce pain and improve movement after knee replacement surgery. About 46 adults aged 50 to 80 will be randomly assigned to receive either real laser therapy or a fake laser treatment …

This study compares a low-volume dose of the numbing drug bupivacaine to the standard volume for a pain block after laparoscopic gallbladder removal. The goal is to see if the lower dose works just as well while reducing the risk of side effects. About 96 adults scheduled for sur…

This study compares two ultrasound-guided nerve blocks—modified thoracolumbar interfascial plane block and quadro-iliac plane block—for pain relief after lower back surgery. About 80 adults undergoing elective lumbar instrumentation will receive one of the two blocks. The goal is…

This study tests whether an extra nerve block during weight-loss surgery can lower pain, nausea, and the need for pain medication in the first three days after surgery. About 200 adults having sleeve gastrectomy or gastric bypass will be randomly assigned to receive either standa…

This study tests whether adding suzetrigine to standard pain relief helps women avoid opioids for the first 3 days after a C-section. About 90 women having scheduled or unscheduled C-sections will receive either suzetrigine or a placebo, along with usual pain medicines. The goal …

This study tests if a safe, non-invasive brain stimulation technique called tDCS can help people recover from knee replacement surgery. About 70 adults scheduled for a knee replacement will use a home-based device before and after surgery. The goal is to see if this approach can …

This study compares two methods of giving a scalp nerve block to children having brain tumor surgery. The standard method uses touch to guide the needle, while the new method uses ultrasound to see the nerves and blood vessels. The goal is to see if ultrasound guidance provides b…

This study looks at whether a simple foot bath can help people feel less pain, sleep better, and be more comfortable after abdominal surgery. About 96 adults who just had surgery will be randomly assigned to get a foot bath or not. Researchers will measure pain, sleep quality, an…

This study compares two pain management methods after total knee replacement surgery. One method uses two nerve blocks, while the other uses a nerve block plus an injection by the surgeon. The goal is to see which approach provides better pain relief during movement 24 hours afte…

This study tests two different machines that pump gas into the belly during laparoscopic sleeve gastrectomy (a weight-loss surgery). The goal is to see if one device causes less pain in the shoulder, neck, chest, and belly after surgery. About 74 adults aged 22 to 65 having plann…

This study compares two devices that inflate the belly during robotic gastric sleeve surgery. The goal is to see which device causes less shoulder, neck, and chest pain after the operation. About 74 adults having planned sleeve gastrectomy will take part. The results could help i…

This study looks at whether being addicted to your smartphone can change how much pain you feel after nose surgery (rhinoplasty) and how much pain medicine you need. Researchers will watch 100 adults aged 18-45 who are having planned nose surgery. No treatment is given—just obser…

This study uses surveys to understand how parents, surgeons, and anesthesiologists feel about using methadone for pain after children's outpatient surgery. Researchers want to see if views differ based on where families live, language, or race. The goal is to gather information, …