CIRRHOSIS

This study tested whether using a health app (PatientBuddy) and a brain-function test (EncephalApp) could help prevent unnecessary hospital readmissions within 30 days for people with cirrhosis. The study involved 232 patients and their caregivers. The goal was to see if tracking…

This study compared two antibiotics (ciprofloxacin and ceftriaxone) given through a vein to treat a serious belly infection called spontaneous bacterial peritonitis in people with liver cirrhosis. The infection is common and can be deadly. The study included 310 adults aged 25-70…

This study tested whether guiding robotic surgery with the vagus nerve could reduce digestive problems like diarrhea and delayed stomach emptying after spleen removal and blood vessel repair. Sixty adults with cirrhosis, an enlarged spleen, and bleeding from high blood pressure i…

This study tested whether an artificial intelligence (AI) program can spot early signs of serious liver disease by analyzing a simple heart test (ECG). Researchers included 279 primary care doctors and their adult patients. The goal was to see if the AI tool leads to more new dia…

This study looked at whether a breath test can help find liver diseases like scarring (fibrosis), severe scarring (cirrhosis), and liver cancer early. Researchers collected breath samples from 56 adults with known or suspected liver problems. They used special machines to analyze…

This study tested a simple strip test called PeriScreen to quickly diagnose infections in the belly fluid of people with cirrhosis. The goal is to speed up diagnosis and improve survival. About 649 adults with cirrhosis and ascites took part. The test was compared to standard lab…

This study tested whether a noninvasive device called FibroScan can accurately measure liver scarring (fibrosis) in children, potentially replacing the standard but painful liver biopsy. Researchers compared the device's readings to biopsy results in 264 children with various liv…

This study tested whether a smartphone app called PatientBuddy could help people with cirrhosis and their caregivers prevent unnecessary hospital readmissions within 30 days after discharge. The app provided tools and support for managing the condition at home. The trial included…

This study tested whether the drug rifaximin can prevent a serious brain condition called hepatic encephalopathy in people with cirrhosis who undergo a TIPS procedure. TIPS helps reduce pressure in the liver but often leads to brain complications. The trial involved 211 participa…

This study looked at whether doxycycline, a common antibiotic, can prevent spontaneous bacterial peritonitis (SBP) in people with cirrhosis. SBP is a serious infection of the fluid in the belly. The study included 841 adults with cirrhosis who were at risk for SBP. Researchers co…

This study tested a sleep medication called lemborexant in 82 adults with liver cirrhosis who had trouble sleeping. The goal was to see if it could improve sleep quality safely. The drug works by blocking wakefulness signals in the brain to promote natural sleep.

This study tested whether a gentle electrical current applied to specific acupoints (like on the hand and leg) can help people with cirrhosis tolerate an urgent, unsedated endoscopy for suspected variceal bleeding. 180 participants were randomly assigned to receive active stimula…

This study tested the safety of two drugs, mirabegron and montelukast, in 78 people with liver cirrhosis who also had overactive bladder and asthma. Researchers wanted to see if these drugs could be used safely in this group. The study focused on side effects and changes in bladd…

This study measured how often hospitalized patients with cirrhosis experience pain. Researchers surveyed 30 adults at one French hospital, asking about pain presence, location, and intensity. The goal was to fill a gap in knowledge, since no French studies had looked at this befo…

This study looked at 742 adults with cirrhosis (serious liver scarring) in French general hospitals to see how many got recommended vaccines for hepatitis A and B, flu, COVID-19, pneumonia, and tetanus/diphtheria/polio. The goal was to find gaps in protection, not to test a new t…

This study checked if a special MRI scan called LiverMultiScan gives the same results when repeated on the same machine or on different machines. 61 adults with various liver diseases were scanned multiple times. The goal was to see if the scan reliably measures liver fat, iron, …

This study compared two methods of liver biopsy—one through a thin needle through the skin (percutaneous) and another using an endoscope through the mouth (EUS-guided)—to see which one patients liked better. 102 adults with chronic liver disease were randomly assigned to one of t…

This study compared two methods for taking liver tissue samples and measuring blood pressure in the liver: one using an endoscope through the mouth (EUS) and the other using a catheter inserted through a neck vein (transjugular). 58 adults with chronic liver disease or portal hyp…

This study looked at whether a heart ultrasound (echocardiography) can help doctors better manage cirrhosis patients who also develop sudden kidney injury. The goal was to see if heart function measurements could predict which patients would not tolerate fluid replacement therapy…

This study looked at how bacteria from the intestines might travel to the liver and blood in people with hepatitis C-related liver disease. Researchers wanted to understand why this happens and if it makes liver disease worse. Thirty adults with stable liver disease participated,…

This study looked at 206 patients with early-stage upper gastrointestinal cancer to find the best treatment for those who also have liver cirrhosis and enlarged veins in the esophagus or stomach. Researchers compared how well and how safely a standard endoscopic surgery worked in…

This study looked at whether watching a video or reading text helps people with cirrhosis learn more about their condition. 218 adults with cirrhosis took a quiz before and after receiving either text or video education. The goal was to see which method improved knowledge the mos…

This study looked at 60 adults with cirrhosis to see if a simple frailty test (Liver Frailty Index) matches actual leg muscle strength. Researchers measured quadriceps strength and checked for malnutrition and frailty using several tools. The goal is to find better ways to spot p…

This study looked at the genetic makeup of liver cancer in 808 patients. The goal was to find common gene changes and patterns that could help doctors better understand the disease. Researchers used tumor samples from patients who had surgery or other treatments. The results may …

This study looked at 82 adults with cirrhosis and portal hypertension (high blood pressure in the liver) to find out how many have minimal hepatic encephalopathy (MHE) — a mild form of brain fog that can affect thinking. Researchers used simple blood tests and thinking exercises …