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Leg strength test may help spot frailty in liver patients

NCT ID NCT06133127

Knowledge-focused Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study of 60 people with cirrhosis measured quadriceps (thigh) strength and compared it to standard frailty and malnutrition scores. The goal was to see if a simple leg strength test could replace more complex frailty assessments. No treatment was given; it was purely an observational study to improve how doctors evaluate frailty in cirrhosis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Nov 2023

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: SUBJECT : * with a diagnosis of liver cirrhosis (regardless of cirrhosis stage and etiology) * under the care of a physician practising in the University Hospital Estaing in Clermont-Ferrand * affiliated to the french social security system Exclusion Criteria: SUBJECT: * with hepatocellular carcinoma * with HIV infection * with hepatic encephalopathy grade ≥ 2 * with cognitive dysfunction * with contraindication for physical activity * with knee pain/knee disorders * pregnant or breastfeeding * under protective supervision (guardianship, curatorship, protection of the court) Inclusion Criteria for healthy volonteers: * male subjects aged 52 to 62 * female subjects aged 42 to 60 * BMI between 20 and 30 kg/m2 * no musculoskeletal problems limiting physical activity * level of physical activity \< 3 hours per week * affiliated to the french social security system Exclusion Criteria for healthy volonteers: * medical or surgical history deemed incompatible with the trial by the investigator * simultaneous participation in a trial involving a drug or medical device, or period of exclusion from such a trial * participants protected by law (under guardianship, conservatorship, or protection of the court)

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cirrhosis

Contacts and locations

Locations

  • CHU clermont-ferrand

    Clermont-Ferrand, France

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