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Can a smartphone app keep cirrhosis patients out of the hospital?

NCT ID NCT03564626

Knowledge-focused Sponsor: Virginia Commonwealth University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether a health app (Patient Buddy and EncephalApp) plus scheduled follow-up calls and visits could reduce avoidable hospital readmissions within 30 days in 232 cirrhosis patients. Patients and their caregivers were trained on the app and received daily contact, counseling, and follow-up. The goal was to see if this extra support helps prevent unnecessary returns to the hospital.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Patient Buddy and EncephalApp (health app) plus scheduled follow-up calls and visits
What this could lead to
If it works, this approach could help cirrhosis patients avoid unnecessary hospital readmissions by improving monitoring and support at home.
What could go wrong
This is a completed trial, but the results are not yet widely confirmed. The app-based approach may not work for all patients, especially those less comfortable with technology.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

232 people

The number who actually took part.

Started

Jun 2018

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Patient Inclusion Criteria: * Cirrhosis patients ≥21 years of age hospitalized for non-elective reasons * Adult caregiver and the patient living in the same house * Able to complete the Patient Buddy training and evaluation * Discharged home from the hospital * Discharge hospital as primary hospital base Caregiver Inclusion Criteria: * Living in same dwelling as patient for the last ≥1 year * Able to complete the Patient Buddy training and evaluation * Familiar with the patient's routine Patient Exclusion Criteria: * Elective hospitalization * Lack of an adult caregiver * Active substance abuse within 1 month of the hospitalization (alcohol use is acceptable provided the patient does not have alcoholic hepatitis during this admission or \<1 month prior to admission) * Unable to perform training or give consent * Patients discharged to hospice, nursing home or extended care facilities * pregnant women * patients with limited English proficiency Caregiver Exclusion Criteria * Unable or unwilling to train or adhere to study guidelines * Unfamiliar with the patient routines * Not in the same house as the patient

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cirrhosis

Contacts and locations

Locations

  • Hunter Holmes McGuire VA Medical Center

    Richmond, Virginia, 23249, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

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