Radiculopathy

This trial tests whether the angle of the needle during an S1 transforaminal epidural steroid injection affects how the medication spreads and how well it relieves pain. About 63 adults with S1 nerve compression from a herniated disc will be randomly assigned to receive the injec…

This study tests whether a structured, internet-based neck exercise program can improve recovery compared to standard prescribed physical activity in people who still have neck disability after anterior cervical spine surgery. Participants are adults who had surgery for cervical …

This study compares two surgical methods for treating lumbar disc herniation, a common cause of leg pain (radiculopathy). One method uses a microscope through a small incision, while the other uses a full endoscope, which may allow an even smaller cut. The trial will look at whet…

Cervical radiculopathy happens when a nerve in the neck is compressed, causing pain, numbness, and weakness in the arm. Researchers are testing whether adding manual therapy to the lower back and sacroiliac joints makes neck-focused manual therapy work better. Adults aged 18 to 5…

Researchers at Cairo University are studying whether a specific exercise program that targets the posterior oblique sling, a network of muscles in the lower back and pelvis, can improve muscle coordination and function in people with lumbosacral radiculopathy. This condition caus…

This study compares two physical therapy techniques—ELDOA (a sustained stretching method) and Spinal Mobilization with Limb Movement (SMWLM)—for treating lumbar radiculopathy, commonly known as sciatica. Thirty-six adults aged 30-50 with mild disc herniation will receive one of t…

This trial tests whether a specialized hands-on therapy called three-dimensional myofascial release, combined with motor control training, can improve how patients perceive their back and reduce pain in lumbar radiculopathy—a condition where a nerve in the lower spine is compress…

This study compares two minimally invasive procedures for people with low back pain that radiates into the leg (radiculopathy) and hasn't improved with conservative care. One treatment injects ozone gas into the spinal disc, while the other uses pulsed radiofrequency to deliver e…

This trial tests whether a traditional Chinese exercise called Ba Duan Jin or a modern sports medicine approach (NASM) better eases pain, improves neck movement, and reduces disability in people with cervical spondylotic radiculopathy, a common cause of neck and arm pain. About 4…

This study compares two non-invasive treatments—high-power laser and pulsed electromagnetic therapy—for reducing pain and improving nerve function in people with lumbar radiculopathy (sciatica from a herniated disc). Sixty participants aged 55-68 will receive one of the therapies…

This trial compares two exercise programs—McKenzie extension exercises versus core stability exercises—each combined with spinal decompression therapy, in adults with disc-related low back pain and leg pain. Forty-two participants aged 25 to 45 with a confirmed disc bulge will be…

This study tests whether adding nerve gliding exercises to standard rehab can reduce pain and improve neck movement, grip strength, and quality of life in people with cervical radiculopathy (a pinched nerve in the neck). The trial plans to enroll 28 adults with disc bulges at spe…

This study compares two common treatments—shockwave therapy and therapeutic ultrasound—each given alongside standard physiotherapy, for people with chronic sciatica. The goal is to see which approach better reduces pain, improves hamstring flexibility, enhances sleep quality, and…

This study looked at whether a steroid injection in the neck (called cervical interlaminar epidural steroid injection) can reduce pain and disability in people with a pinched nerve in the neck (cervical radiculopathy). 98 adults with neck and arm pain that did not improve with ot…

This completed study compared two minimally invasive surgeries for herniated discs: full endoscopic lumbar discectomy (FELD) and microdiscectomy (MD). Researchers enrolled 200 adults aged 18-85 with single-level disc herniation and sciatica. The goal was to see which technique pr…

This study tested whether adding a gentle nerve-stretching technique called neurodynamic mobilization to standard physical therapy helps people with cervical radiculopathy—a pinched nerve in the neck causing arm pain and weakness. Fifty adults received either standard therapy alo…

This study compared two physical therapy approaches—McKenzie exercises and neural flossing—in 28 adults aged 25 to 60 with acute cervical radiculopathy (neck pain that travels down the arm). The goal was to see which method better reduces pain and improves daily function. Results…

This study tested whether gabapentin, a nerve pain medication, provides better short-term pain relief than a placebo for people hospitalized with acute sciatica caused by a herniated disc. 144 adults received either gabapentin or placebo on top of their usual pain treatment for t…

This study looked at whether steroid injections into the spine can reduce pain and improve daily function in people with lower back and leg pain from a herniated disc. 221 adults who had not improved with other treatments received the injections and were followed for three months…

This study tested two exercise techniques—dynamic stretching and nerve gliding—in 72 adults with lumbar radiculopathy (nerve-related back pain). Both groups also received standard physiotherapy. The goal was to see which approach better reduced pain and improved daily function ov…

This study tested two different hands-on treatments for people with lower back pain that shoots down the leg (lumbar radiculopathy). Twenty adults received either spinal mobilization with leg movement or nerve gliding exercises for six weeks. The goal was to see which therapy bet…

This study tested two types of nerve mobilization exercises—slider and tensioner—in 36 adults with chronic neck pain from cervical radiculopathy. Participants received standard care plus one of the two techniques. The goal was to see which better reduces pain, improves neck movem…

This study looked at whether High Tone Power Therapy can help people with long-term lower back pain that travels down one leg. 52 adults aged 35 to 50 with a herniated disc took part. The therapy aims to reduce pain, improve movement, and boost quality of life.

This study looked at whether adding physical therapy (like heat, ultrasound, and TENS) to a standard steroid injection helps people with back and leg pain caused by a herniated disc. 76 adults with pain lasting more than 3 months were split into two groups: one got only the injec…

This study tested whether immersive virtual reality (VR) can help reduce pain, improve balance, and restore neck movement in people with cervical radiculopathy — a condition where a pinched nerve in the neck causes pain and numbness down one arm. 42 adults aged 35-50 took part. S…

This study tested whether adding electrical muscle stimulation to standard exercise therapy helps young adults with cervical radiculopathy (pinched nerve in the neck causing pain, numbness, or weakness). Fifty participants aged 18-29 did 12 sessions over 6 weeks, with one group r…

This study compared hybrid tele-rehabilitation (online sessions via Zoom) to standard clinic-based therapy for 32 adults with lumbar radiculopathy (sciatica from a slipped disc). Participants did exercises like lumbar stabilization and nerve mobilization. The trial measured pain,…

This study tested whether a gentle hands-on therapy called Maitland mobilization, added to standard physical therapy, can improve walking patterns in people with lumbosacral radiculopathy (nerve pain in the lower back and leg). 46 adults aged 35-45 with chronic pain took part. Re…

This study looked at whether combining McKenzie exercises with nerve-gliding moves could help people with cervical radiculopathy—a pinched nerve in the neck causing arm pain. 46 adults aged 35-50 with a bulging disc in the lower neck took part. Over 4 weeks, they did these exerci…

This study tested two physical therapy approaches for people with chronic low back pain caused by a pinched nerve, where the spine also shifts to one side. 28 adults aged 30-60 took part. The goal was to see if the McKenzie method (a specific exercise technique) works better than…

This study looked at a procedure called epiduroscopic adhesiolysis, which uses a tiny camera to see inside the spine and break up scar tissue, for people with long-term back and leg pain. Researchers compared results in 141 adults who had prior back surgery and those who did not.…

This study tested whether giving a steroid (dexamethasone) during minimally invasive back surgery reduces pain and disability afterward. 90 adults with a herniated disc in the lower back took part. Half received the steroid during surgery, half got a saltwater placebo. Researcher…

This study looked at whether a set of head and neck exercises (called Cawthorne-Cooksey exercises) can improve neck awareness and daily function in people with long-term neck pain from a pinched nerve. 54 adults aged 30-45 with mild to moderate neck disability and dizziness took …

This study tested whether adding a painless magnetic stimulation treatment to standard manual therapy (like massage and stretching) helps people with sciatica caused by a herniated disc. Forty adults were split into two groups: one got manual therapy alone, the other got manual t…

This study compared two injection treatments for neck pain caused by cervical radiculopathy. Seventy adults who did not get better with standard care were randomly assigned to receive either an ultrasound-guided retrolaminar block or a fluoroscopy-guided epidural injection. The g…

This early-stage study tested whether an injection called STA363 is safe for people with sciatica from a herniated (slipped) disc. Twenty-five adults received either the study drug or a placebo injection into the disc. Researchers checked for side effects and measured changes in …

This completed Phase 2 trial tested the drug VX-548 (Suzetrigine) in 218 adults with painful lumbosacral radiculopathy, a condition where a pinched nerve in the lower back causes leg pain. The study compared the drug to a placebo to see if it safely reduces leg pain and improves …

This study tested whether high-power laser therapy can reduce pain and disability in people with sciatica caused by a herniated disc. Thirty-six adults with at least 12 weeks of symptoms received either real or sham laser treatments. The goal was to see if the laser improves pain…

Researchers at Cairo University are investigating whether forward head posture, common in people who use smartphones for hours a day, is linked to cervical radiculopathy, a condition where neck nerves become irritated and cause pain or numbness in the arm. The study enrolls 120 a…

This study tested whether letting doctors practice on a 3D virtual reality model of a patient's spine before a real injection makes the procedure faster and safer. Thirty adults with difficult-to-treat back pain took part. The main goal was to see if VR training reduced procedure…

This study tested whether using a screening questionnaire called the STarT Back Tool helps doctors tailor low back pain treatment for military members. 290 adults aged 18-50 with low back pain were randomly assigned to either risk-stratified care or usual care. The goal was to se…

This study looked at 64 adults with lower back and leg pain caused by a herniated disc. Researchers measured how well participants could sense their hip joint position and compared it to any pelvic asymmetry. The goal was to understand the connection between pelvic alignment, bod…

This study followed 50 people with chronic low back pain for 10 years after they had a procedure that punctured a spinal disc. Researchers used MRI scans to check if the punctured disc wore out faster than expected. The main goal was to see if the puncture itself caused extra dam…

This study surveyed 54 Belgian spinal surgeons about how they advise patients on returning to work after lumbar surgery for leg pain caused by nerve compression. The goal was to understand current practices, barriers, and what helps surgeons give good return-to-work guidance. The…

This study reviewed records of 107 adults who received steroid injections in the neck for arm and neck pain caused by a pinched nerve. The goal was to find out which patient traits or injection details were linked to better pain relief at 6 months. By identifying these predictors…

This study looked at 264 people with chronic lower back and leg pain caused by a pinched nerve. Researchers wanted to see if routine blood test results could predict who would get good pain relief from a combination of two treatments: a nerve block and a short electrical pulse to…

This study looked back at the medical records of 90 adults with neck and arm pain caused by a pinched nerve. Researchers wanted to see if MRI scans could predict who would get good pain relief from a procedure called a stellate ganglion block, where numbing medicine is injected n…

This study looked at whether having low magnesium in the body makes steroid injections for back pain less effective. Researchers followed 118 people with back pain who received these injections and measured their pain and disability levels. The goal was to see if magnesium defici…

This completed study with 92 people tested whether a measure called perfusion index (a way to check blood flow) can predict how well a nerve block (erector spinae plane block) relieves chronic neck pain from conditions like herniated discs or spinal narrowing. Researchers tracked…

This study tested whether doctors reviewing post-procedure X-ray images with patients after spine injections improves satisfaction. 141 adults with leg pain from pinched nerves participated. Two weeks later, patients filled out surveys about their care experience and how much the…

This study looked at 80 adults with cervical radiculopathy (a pinched nerve in the neck) to see how their level of neck disability relates to their ability to move their neck in different directions. Researchers measured range of motion in six directions and compared it to disabi…