Laser light could ease sciatica pain without surgery
NCT ID NCT06151704
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether high-power laser therapy can reduce pain and disability in people with sciatica caused by a herniated disc. Thirty-six adults with at least 12 weeks of symptoms received either real or sham laser treatments. The goal was to see if the laser improves pain, movement, and daily function without the side effects of drugs or surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- high-power laser therapy
- What this could lead to
- If effective, this could provide a non-invasive, side-effect-free option to ease pain and improve mobility for people with sciatica from a herniated disc.
- What could go wrong
- This is a small, completed trial with only 36 participants. Results may not apply to everyone, and the benefit over sham laser is uncertain until published.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
36 people
The number who actually took part.
- Started
-
May 2022
- Finished
-
Dec 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
25 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The diagnosis of radicular low back pain, originating from an intervertebral disc herniation between the fourth lumbar and first sacral vertebrae, is confirmed by a neurosurgeon * A minimum of 12 weeks have elapsed since the onset of symptoms. The patient experiences persistent pain or paraesthesia (numbness and/or tingling) in the lower back or both limbs, attributable to the herniation of the lumbar intervertebral disc impinging on the nerve root dermatome * Magnetic Resonance Imaging (MRI) scans of the patients reveal either protrusion or extrusion disc herniation. Exclusion Criteria: * Local or systemic infection, rheumatic disease, diabetes * Vertebral and sacroiliac joint dysfunction (Gillette test positive) * Pregnancy * History of previous surgery in the area * Patients with MRI of spinal canal stenosis or spondylolisthesis * Patients with vascular disorders, cancer and tumors and synovial cysts * History of physiotherapy for at least the last 12 weeks * sciatic nerve Contusion * psychiatric illnesses * Active trigger point of gluteus minimus muscle (diffuse sciatica-like pain)
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Radicular low back pain due to lumbar intervertebral disc herniation are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
School of Rehabilitation Sciences, Iran University of Medical Sciences
Tehran, Tehran Province, P.O. Box 4391-15875, Iran
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New needle technique could pinpoint painful nerves more accurately
- Can mirror exercises beat standard physio for sciatica?
- Could a common steroid plus ibuprofen ease shooting back pain faster?
- Blood test may predict pain treatment success
- Back pain injection satisfaction: does anxiety or sedation matter?
- New therapy eases chronic back and leg pain in small study