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Back pain breakthrough? study tests combo therapy for sciatica

NCT ID NCT07467421

Symptom relief Sponsor: Ankara Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding physical therapy (like heat, ultrasound, and TENS) to a standard steroid injection helps people with back and leg pain caused by a herniated disc. 76 adults with pain lasting more than 3 months were split into two groups: one got only the injection plus home exercises, the other got the injection plus 10 sessions of physical therapy. Researchers measured pain, disability, and mood at the start, 1 hour after injection, and at 1 and 3 months to see if the combo offered extra relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

76 people

The number who actually took part.

Started

Jun 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged between 18 and 65 years. * Diagnosis of lumbar disc herniation confirmed by physical examination and Magnetic Resonance Imaging (MRI) within the last 6 months. * Presence of acute radicular pain symptoms lasting more than 3 months. * Failure to respond to conservative medical treatments (e.g., medication, rest). * Voluntary participation and signed written informed consent. Exclusion Criteria: * History of previous lumbar spinal surgery. * Presence of progressive motor deficits or Cauda Equina Syndrome. * Pregnancy or breastfeeding. * Diagnosis of malignancy, inflammatory rheumatic diseases, or neurodegenerative disorders. * Severe obesity (Body Mass Index \> 40 kg/m²). * Known allergy to injection materials (Lidocaine, Betamethasone). * Active local or systemic infection. * Presence of bleeding disorders or use of anticoagulants that cannot be safely discontinued. * Having received an epidural steroid injection or a clinical physical therapy program within the last 3 months.

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Conditions

The condition(s) this trial relates to.

Intervertebral Disc Displacement Low Back Pain radiculopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Low back pain (LBP) Lumbar disc herniation with radiculopathy

Contacts and locations

Locations

  • Ankara Training and Research Hospital

    Ankara, Ankara, 06230, Turkey (Türkiye)

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