Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can back surgery be Pain-Free without opioids?

NCT ID NCT07489001

Symptom relief Sponsor: Marmara University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether avoiding opioids during back surgery can still control pain and reduce side effects like nausea and constipation. About 75 adults having elective lumbar spine surgery will be placed into one of three groups based on their anesthesia plan. The goal is to see if opioid-free methods work just as well or better than traditional opioid-based anesthesia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 75 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients aged 18 to 75 years undergoing elective lumbar spine surgery for conditions such as lumbar spinal stenosis, lumbar disc herniation, degenerative spondylolisthesis, or lumbar disc degeneration at Marmara University Pendik Training and Research Hospital. All participants are surgical patients who meet the clinical indication for lumbar spinal procedures. No healthy volunteers are included. Patients are assigned to one of three observational cohorts based on the anesthesia technique chosen by the attending anesthesiologist in routine clinical practice.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 75 years * Elective surgery only * Scheduled for elective lumbar spinal surgery (lumbar spinal stenosis and/or lumbar disc herniation) * ASA physical status I-III * No previous lumbar spine surgery * Able to provide written informed consent * BIS monitoring available and recorded * Ability to comply with postoperative pain assessment (NRS/VAS) * Stable hemodynamic status preoperatively Exclusion Criteria: * Age younger than 18 or older than 75 * Inability or unwillingness to provide informed consent * Severe psychiatric disease or cognitive impairment * Emergency surgery cases * BMI \> 40 kg/m² * Pregnancy * Uncontrolled hypertension, arrhythmia, or severe cardiac disease * Renal failure * Chronic beta-blocker use * Coagulation disorders * Chronic alcohol dependence or substance use * Neurological deficits affecting perception of pain * Chronic pain syndrome (fibromyalgia, chronic LBP \> 3 months) * Chronic gabapentinoid use * Anemia * Known allergy to any anesthetic or analgesic agents used in the study * Local infection at the intended ESP block injection site * Intraoperative change in anesthetic technique that deviates from initial planned management * Pediatric patients (\<18 years)

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Lumbar degenerative spondylolisthesis are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder lumbar disk herniation, susceptibility to lumbar spinal stenosis Pain, Postoperative spinal stenosis spondylolisthesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lumbar degenerative spondylolisthesis Lumbar disc degeneration Lumbar disc herniation with radiculopathy Lumbar spinal stenosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Marmara university hospital

    RECRUITING

    Istanbul, Maltepe, 34722, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.