Dental pulp disorder
MONDO:0003394A disease involving the dental pulp.
Also known as: dental pulp disease, dental pulp disease or disorder, dental pulp disorder, disease of dental pulp, disease or disorder of dental pulp, disorder of dental pulp
277 clinical trials for this condition and its sub-types, 37 tagged with Dental pulp disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Dental pulp disorder
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Pulpitis 191 trials
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Dental pulp necrosis 67 trials
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Exposure, dental pulp 13 trials
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Dental pulp calcification 1 trial
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Secondary dentine 1 trial
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Pulp degeneration 0 trials
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Pulp erosion 0 trials
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Can sonic and laser devices revolutionize root canal healing?
Disease control CompletedThis trial tests whether two newer root canal cleaning devices—GentleWave and Waterlase—can improve healing compared to the standard ultrasonic method. About 120 people needing a root canal will be randomly assigned to one of the three techniques. The study tracks how well the in…
Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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Dental fillings that soothe the tooth nerve? new trial tests bioactive materials
Disease control CompletedThis trial compares different bioactive restorative materials and placement techniques to see how they affect the health of the tooth's pulp (nerve) after treating deep cavities. Researchers will measure inflammatory markers in the fluid around the tooth and track post-treatment …
Sponsor: Dina Ashraf • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Root canal showdown: one visit or two? new study has answers
Disease control CompletedThis study looked at whether a root canal for an infected tooth with an abscess can be done in one visit instead of two. Fifty-nine adults received either a single-visit treatment or a two-visit treatment with a calcium hydroxide medication placed in between. After 12 months, bot…
Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New study finds best way to save decayed baby teeth in kids
Disease control CompletedThis study looked at 120 healthy children aged 4-7 with deep cavities in their baby molars. Dentists removed the decay and used one of three special materials to cover the nerve, then sealed the tooth with either a filling or a metal crown. The goal was to see which combination w…
Sponsor: British University In Egypt • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Can a handheld device perfectly measure root canals? study puts it to the test
Diagnosis CompletedThis study evaluates how accurately the Root ZX3 electronic apex locator measures the working length of root canals in single-rooted teeth that need to be extracted. Researchers compare the device's measurements with microscopic measurements taken after extraction, which serve as…
Sponsor: Riyadh Elm University • Aim: Diagnosis
Last updated Jul 10, 2026 00:00 UTC
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Dentists put cold, heat, and electric tooth tests to the test
Diagnosis CompletedThis study tested how well cold, heat, and electric pulp tests detect tooth nerve health in 175 adults needing root canals. Researchers compared test results to direct observation of nerve bleeding during treatment. The goal was to find which test is most accurate for diagnosing …
Sponsor: Istanbul University • Aim: Diagnosis
Last updated Jun 27, 2026 09:09 UTC
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Can a laser beam replace painkillers after dental surgery?
Symptom relief CompletedThis trial asks whether photobiomodulation — a type of low-level laser therapy — can lessen pain and swelling after endodontic (root-end) surgery. Thirty-four adults needing surgery on an upper tooth will be randomly assigned to receive either the laser treatment or a sham proced…
Sponsor: University of Nove de Julho • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
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Can a different rinse cut pain after root treatment in kids?
Symptom relief CompletedThis trial compares two irrigation solutions used during regenerative endodontic treatment for immature permanent teeth with infection. Forty children aged 9 to 16 will receive either octenidine or EDTA as a rinse, and their pain levels will be tracked for a week. The goal is to …
Sponsor: TC Erciyes University • Aim: Symptom relief
Last updated Jul 25, 2026 00:00 UTC
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Lasers vs. needles: which root canal hurts less?
Symptom relief CompletedThis study tested whether using special lasers during root canal treatment can lower pain afterward compared to standard methods. Forty-five adults with infected front teeth were split into three groups: one got standard cleaning, another got a combination of two lasers, and the …
Phase 2 • Sponsor: Future University in Egypt • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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VR headsets could stop gagging at the dentist
Symptom relief CompletedThis study tested whether watching a short animated movie through a VR headset can help control the gag reflex and reduce anxiety in adults during dental X-rays. Thirty patients each had two X-rays: one with standard care and one with VR distraction. Researchers measured gagging …
Sponsor: Qassim University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Which root canal filling hurts least? new study has answers
Symptom relief CompletedThis study tested three different root canal filling materials in 54 people with inflamed tooth pulp to see which caused the least pain after a single-session root canal. Patients rated their pain over 7 days. The goal is to find a material that makes root canals more comfortable…
Sponsor: TC Erciyes University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Glue or chemical? study tests best way to stop bleeding after tooth surgery
Symptom relief CompletedThis study tested two different materials—surgical glue and ferric sulfate—to control bleeding during root-end surgery in 34 patients with infected tooth roots. Researchers measured how well each agent stopped bleeding, how much pain patients felt afterward, and their quality of …
Sponsor: University of Turin, Italy • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Chill out: cold saline may soothe root canal pain
Symptom relief CompletedThis study looked at whether applying cold (cryotherapy) after a root canal can lower pain in people with a tooth nerve infection (irreversible pulpitis). 45 adults with a lower premolar tooth were split into three groups: one got a cold saline injection near the tooth, one got c…
Sponsor: October 6 University • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Root canal bacteria under the microscope: new study aims to improve treatment
Knowledge-focused CompletedThis pilot study looked at bacteria in root canal infections, comparing painful and painless cases. Researchers used DNA testing to identify bacteria before and after cleaning with two different strengths of sodium hypochlorite. The goal was to see how well the cleaning removes b…
Sponsor: Hasanuddin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Common painkillers may skew tooth nerve tests, study finds
Knowledge-focused CompletedThis study tested whether taking common painkillers like paracetamol or ibuprofen before a dental pulp sensitivity test changes the results. 184 healthy adults received either a painkiller or a placebo, and their tooth nerve responses were measured. The goal is to help dentists a…
Sponsor: Pakistan Institute of Medical Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Dental Students' posture under the microscope: a fatigue study
Knowledge-focused CompletedThis study looked at how dental students hold their bodies while doing root canal work. Ten students were recorded on video for 5 minutes, and their posture and muscle fatigue were analyzed. The goal was to understand how their working positions might lead to pain or injury. This…
Sponsor: Universidad Europea de Madrid • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Tooth transplant breakthrough: new method aims to restore blood flow
Knowledge-focused CompletedThis study looked at a new way to transplant mature teeth that might help them regain blood supply. Researchers reviewed the outcomes of 16 people who had this procedure. The goal was to see if the teeth survived and if blood flow returned.
Sponsor: Medical University of Graz • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Brain waves may reveal who will feel more pain after root canal
Knowledge-focused CompletedThis study looked at whether measuring brain waves before a root canal can help predict how much pain a person will feel afterward. One hundred adults with tooth pain took part. Researchers recorded their brain activity at rest and then asked them to rate their pain after treatme…
Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Tooth enamel defect study probes hidden inflammation in kids
Knowledge-focused CompletedThis study looked at children aged 8 to 13 with a common enamel defect called Molar-Incisor Hypomineralization (MIH). Researchers measured inflammatory markers in the pulp (nerve) of affected teeth and compared them to healthy teeth. The goal was to better understand how MIH affe…
Sponsor: Marmara University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC