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Chill out: cold saline may soothe root canal pain

NCT ID NCT06304259

First seen Nov 19, 2025 · Last updated May 20, 2026 · Updated 22 times

Summary

This study looked at whether applying cold (cryotherapy) after a root canal can lower pain in people with a tooth nerve infection (irreversible pulpitis). 45 adults with a lower premolar tooth were split into three groups: one got a cold saline injection near the tooth, one got cold saline inside the tooth canal, and one got standard care. Pain levels were checked at 12, 24, and 48 hours after treatment. The goal was to find a simple way to reduce discomfort after the procedure.

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Contacts and locations

Locations

  • Faculty of Dentistry, Ain shams University

    Cairo, 4543070, Egypt

Conditions

Explore the condition pages connected to this study.