Chill out: cold saline may soothe root canal pain
NCT ID NCT06304259
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether applying cold (cryotherapy) after a root canal can lower pain in people with a tooth nerve infection (irreversible pulpitis). 45 adults with a lower premolar tooth were split into three groups: one got a cold saline injection near the tooth, one got cold saline inside the tooth canal, and one got standard care. Pain levels were checked at 12, 24, and 48 hours after treatment. The goal was to find a simple way to reduce discomfort after the procedure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Dentistry, Ain shams University
Cairo, 4543070, Egypt
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