Chill out: cold saline may soothe root canal pain
NCT ID NCT06304259
First seen Nov 19, 2025 · Last updated May 20, 2026 · Updated 22 times
Summary
This study looked at whether applying cold (cryotherapy) after a root canal can lower pain in people with a tooth nerve infection (irreversible pulpitis). 45 adults with a lower premolar tooth were split into three groups: one got a cold saline injection near the tooth, one got cold saline inside the tooth canal, and one got standard care. Pain levels were checked at 12, 24, and 48 hours after treatment. The goal was to find a simple way to reduce discomfort after the procedure.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Faculty of Dentistry, Ain shams University
Cairo, 4543070, Egypt
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