Chill out: cold saline may soothe root canal pain

NCT ID NCT06304259

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether applying cold (cryotherapy) after a root canal can lower pain in people with a tooth nerve infection (irreversible pulpitis). 45 adults with a lower premolar tooth were split into three groups: one got a cold saline injection near the tooth, one got cold saline inside the tooth canal, and one got standard care. Pain levels were checked at 12, 24, and 48 hours after treatment. The goal was to find a simple way to reduce discomfort after the procedure.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dentistry, Ain shams University

    Cairo, 4543070, Egypt

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