Could a simple steroid shot make root canals less painful?

NCT ID NCT07699315

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This trial investigates whether a single injection of dexamethasone, a steroid, given before a root canal can lower pain during the procedure. It includes adults with severe tooth pain from symptomatic irreversible pulpitis. Participants receive either dexamethasone or a placebo, and pain levels are measured using a standard scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dexamethasone
What this could lead to
If it works, this could offer a simple way to make root canal treatments less painful for many patients.
What could go wrong
This is a small, early-phase study, so results may not apply to everyone. Dexamethasone may not reduce pain for all patients, and there are risks with any injection.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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