Chill after the drill: could cold saline soothe root canal pain?
NCT ID NCT07663227
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether using a cold saline rinse after ultrasonic cleaning during a root canal can lower pain afterward. Adults with an inflamed tooth nerve will get either ultrasonic cleaning alone or followed by a cold saline flush. Pain levels are tracked for three days after the procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ultrasonic activated irrigation and intracanal cryotherapy (cold saline)
What this could lead to
If effective, this approach could offer a simple, low-cost way to reduce pain after root canal treatment, improving patient comfort.
What could go wrong
This is a small, early-stage trial with 60 participants, so results may not apply to everyone. The pain reduction may be minimal or not clinically significant.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.