Chill after the drill: could cold saline soothe root canal pain?
NCT ID NCT07663227
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether using a cold saline rinse after ultrasonic cleaning during a root canal can lower pain afterward. Adults with an inflamed tooth nerve will get either ultrasonic cleaning alone or followed by a cold saline flush. Pain levels are tracked for three days after the procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ultrasonic activated irrigation and intracanal cryotherapy (cold saline)
- What this could lead to
- If effective, this approach could offer a simple, low-cost way to reduce pain after root canal treatment, improving patient comfort.
- What could go wrong
- This is a small, early-stage trial with 60 participants, so results may not apply to everyone. The pain reduction may be minimal or not clinically significant.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Other studies related to the condition(s) this trial covers.
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