Chilling the root: could cryotherapy cool Post-Dental pain?
NCT ID NCT07771816
First seen Aug 18, 2026 · Last updated Aug 18, 2026
Summary
This trial tests whether applying cryotherapy (cold therapy) along with different concentrations of sodium hypochlorite irrigation during vital pulp therapy can reduce post-operative pain in permanent mandibular molars. Adults aged 15-40 with symptomatic irreversible pulpitis will undergo the procedure, and their pain levels will be measured using a standard pain scale. The goal is to see if adding cold therapy to the irrigation improves pain control compared to standard irrigation alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Sodium hypochlorite irrigation with and without cryotherapy during vital pulp therapy
- What this could lead to
- If effective, this approach could offer a simple, low-cost way to reduce pain after root canal procedures, improving patient comfort and recovery.
- What could go wrong
- This is a very small early-stage trial, so results may not apply broadly. Pain relief may not differ significantly, and the procedure carries standard risks like infection or tissue irritation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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faculty of oral and dental medicine Future University in Egypt
Cairo, Cairo Governorate, 11835, Egypt
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