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Brain waves may reveal who will feel more pain after root canal

NCT ID NCT07445633

Knowledge-focused Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether measuring brain waves before a root canal can help predict how much pain a person will feel afterward. One hundred adults with tooth pain took part. Researchers recorded their brain activity at rest and then asked them to rate their pain after treatment. The goal was to see if certain brain wave patterns are linked to higher pain levels.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Jan 2022

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of patients seeking dental treatment at the Department of Endodontics, Faculty of Dentistry, Ain Shams University.

Ages

20 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: 1. Patient's age ranges from 20-40. 2. Vital lower first molar with signs and symptoms of acute irreversible pulpitis and indicated for single visit root canal treatment. 3. Patients that had not received any medicinal therapy after endodontic treatment. 4. Patients who are mentally and physically capable to record pain intensity estimated every 6 hours after endodontic treatment using VAS. Exclusion criteria: 1. Patient systemic disease or neurogenic disease that contraindicates the use of the EEG or have sensitivity to the electrode material. 2. Cases that root canal treatment could not be finished in a single visit such as teeth with apical periodontitis, pulpal necrosis, chronic apical abscess. 3. Patients who took analgesics within 24 hours after endodontic treatment.

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Conditions

The condition(s) this trial relates to.

dental pulp disorder pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pulp disease, dental

Contacts and locations

Locations

  • Ain Shams University

    Cairo, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.