Zagazig University
Clinical trials sponsored by Zagazig University, explained in plain language.
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New study tests safer bleeding control for cesarean scar surgery
Disease control CompletedThis study looked at 30 women having laparoscopic surgery to fix a cesarean scar niche, a pocket in the uterine wall that can cause symptoms. It compared injecting a drug called vasopressin into the uterus versus temporarily clamping the uterine arteries to reduce blood loss duri…
Phase: PHASE2 • Sponsor: Zagazig University • Aim: Disease control
Last updated May 17, 2026 04:16 UTC
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Stent vs. surgery: new hope for kids with esophageal stricture?
Disease control CompletedThis study tested whether a special stent (normally used in bile ducts) can help children whose esophagus has narrowed, making swallowing difficult. Forty children were randomly assigned to get the stent or standard surgery. The main goal was to see if the narrowing comes back. T…
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Mesh fix for hidden hernias during sleeve surgery shows promise
Disease control CompletedThis study looked at 20 adults who had weight loss surgery (sleeve gastrectomy) and were also found to have a hiatal hernia. Surgeons repaired the hernia using a mesh during the same operation. The main goal was to see how often the hernia came back after this combined procedure.
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New fix for twisted bowel shows promise in High-Risk patients
Disease control CompletedThis study tested a new, less invasive procedure to prevent the sigmoid colon from twisting again in people who have had repeated episodes. The procedure uses a needle to fix the colon in place through the skin. The trial included 66 high-risk surgical patients aged 16 to 80. The…
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New 'Sandwich' mesh technique shows promise for tough back hernias
Disease control CompletedThis study tested a new surgical method called 'sandwich mesh repair' for a rare type of hernia that happens after surgery on the lower back. Ten adults with this hernia received the procedure. The main goal was to see if the hernia came back, and the study also tracked fluid bui…
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Which surgery is better for pilonidal sinus? new study compares recovery and sexual function.
Disease control CompletedThis study compared two surgical methods (Karydakis and Limberg flap) for treating pilonidal sinus, a painful cyst near the tailbone. 352 sexually active adults who also drove a car took part. Researchers measured how each surgery affected sexual function and driving ability afte…
Sponsor: Zagazig University • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Smarter mesh design cuts hernia repair risks
Disease control CompletedThis study tested a new mesh design for open inguinal hernia repair in 100 men. The new method uses a smaller mesh placed under a protective layer to avoid nerve contact, aiming to reduce chronic pain and hernia recurrence. Results suggest fewer complications and better outcomes …
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated May 04, 2026 16:22 UTC
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Blood test may replace surgery for endometriosis diagnosis
Diagnosis CompletedThis study looked at whether measuring two tiny molecules (microRNAs) in the blood can accurately diagnose early-stage endometriosis, a painful condition that can cause infertility. Researchers compared blood test results to findings from standard laparoscopic surgery in 60 women…
Phase: NA • Sponsor: Zagazig University • Aim: Diagnosis
Last updated May 15, 2026 11:57 UTC
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Early iron levels may flag diabetes risk in pregnancy
Diagnosis CompletedThis study looked at whether measuring ferritin (a marker of iron stores) early in pregnancy could predict which women would later develop gestational diabetes. Researchers followed 556 pregnant women, checking their ferritin, transferrin, and hemoglobin levels at the start of pr…
Sponsor: Zagazig University • Aim: Diagnosis
Last updated May 11, 2026 20:47 UTC
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Laser precision may tame tricky cataract surgeries
Symptom relief CompletedThis study tested a special laser to create a precise opening in the lens capsule during cataract surgery for people with swollen (intumescent) cataracts. The goal was to see if the laser could make the procedure safer and more accurate than the standard manual method. Twenty-fou…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 17, 2026 04:41 UTC
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Shorter radiation course shows promise for breast cancer patients
Symptom relief CompletedThis study looked at two different radiation schedules for women with early-stage breast cancer after breast-conserving surgery. One group received a very short course of radiation over 1 week, while the other received a slightly longer course over 3 weeks. The goal was to compar…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 17, 2026 04:39 UTC
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Can your own blood help fade stretch marks?
Symptom relief CompletedThis study tested two treatments made from a person's own blood—platelet-rich fibrin (PRF) and platelet-rich plasma (PRP)—alone or with microneedling, to improve the appearance of stretch marks. Thirty adults received different treatments on each side of their body over five sess…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 17, 2026 04:35 UTC
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Spine surgery pain relief showdown: which Add-On works best?
Symptom relief CompletedThis study tested whether adding midazolam or fentanyl to a standard epidural painkiller (bupivacaine plus dexamethasone) helps people recover more comfortably after lower back surgery. One hundred adults undergoing elective lumbar spine fixation took part. The main goal was to s…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 17, 2026 04:35 UTC
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New pain relief method tested for obese patients after chest surgery
Symptom relief CompletedThis study tested two methods to control pain after chest surgery in 102 obese patients. One group received a numbing injection near the spine (nerve block), while the other got pain medicine through an IV. The goal was to see which approach worked better and was safer for this s…
Phase: PHASE4 • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 17, 2026 04:34 UTC
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New spray device may replace needles for endoscopy sedation
Symptom relief CompletedThis study tested a new device that numbs the throat and esophagus with topical anesthesia, comparing it to standard IV sedation (propofol and ketamine) for upper GI endoscopy. Sixty adults undergoing elective endoscopy were enrolled. The goal was to see if the topical method cou…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 17, 2026 04:33 UTC
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Digital support boosts cancer coping skills
Symptom relief CompletedThis study tested an online educational and support program to help cancer patients better manage their symptoms and cope emotionally. 212 adults with different cancers who were receiving chemotherapy took part. The program included online lessons, interactive sessions, and digit…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Cheaper drug may improve sinus surgery outcomes
Symptom relief CompletedThis study tested two drugs, dexmedetomidine and nitroglycerin, to see which one better reduces bleeding and improves the surgeon's view during sinus surgery. 66 adults having elective sinus surgery took part. The goal was to find a safer, more cost-effective way to manage bleedi…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Can melatonin calm surgery stress as well as heart drugs?
Symptom relief CompletedThis study looked at 112 adults having sinus surgery to see if oral melatonin works as well as two intravenous heart medications (metoprolol and dexmedetomidine) at reducing stress from breathing tube placement and improving the surgeon's view. Participants were randomly assigned…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 14, 2026 12:05 UTC
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New pain block helps rib fracture patients breathe easier
Symptom relief CompletedThis study tested two different ultrasound-guided nerve blocks to see which one better controls pain and improves lung function in people with multiple broken ribs. Fifty adults with at least three rib fractures received one of the two blocks. The goal was to find a better way to…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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New pain combo may reduce opioid need after hip surgery
Symptom relief CompletedThis study tested two different pain-relief mixtures given as a nerve block before hip surgery. One group received nalbuphine with bupivacaine, the other dexamethasone with bupivacaine. The goal was to see which combination provided longer pain relief and reduced the need for ext…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC
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New shoulder block spares breathing muscle, study finds
Symptom relief CompletedThis study tested two new nerve block methods for shoulder surgery pain that aim to avoid paralyzing the diaphragm (the main breathing muscle), a common side effect of the standard block. 87 adults having shoulder surgery were enrolled. The new blocks target nerves farther from t…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 11, 2026 20:38 UTC
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New combo therapy tames brain injury storms in ICU patients
Symptom relief CompletedThis study tested two combinations of treatments for 'neurostorming' — sudden, severe stress reactions after traumatic brain injury. 205 critically ill patients received a nerve block (stellate ganglion block) plus either dexmedetomidine or low-dose ketamine. The goal was to calm…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 06, 2026 16:13 UTC
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Dietary change offers relief for IBS sufferers
Symptom relief CompletedThis study tested whether a low-FODMAP diet helps people with irritable bowel syndrome (IBS) feel better. 183 adults with IBS were split into two groups: one learned about the diet, the other did not. Over six months, researchers tracked symptoms and quality of life to see if the…
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated May 01, 2026 16:00 UTC
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Frailty linked to higher risk of rectal prolapse returning in seniors
Knowledge-focused CompletedThis study looked at 342 older adults (aged 60 and above) who had surgery for severe rectal prolapse. The main goal was to see if being frail made it more likely for the prolapse to come back. Researchers tracked patients to understand this connection, aiming to improve care for …
Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 17, 2026 04:35 UTC
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Chest fluid test may help doctors decide when to take patients off ventilators
Knowledge-focused CompletedThis study looked at whether measuring the amount of fluid in the chest (called thoracic fluid content) can help doctors know when it's safe to take a patient off a breathing machine. The researchers studied 120 critically ill adults who had been on a ventilator for more than 48 …
Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 17, 2026 04:17 UTC
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Staples or stitches? study compares best way to repair intestines in emergencies
Knowledge-focused CompletedThis study looked at 90 emergency surgery patients who needed intestinal repair. Doctors compared two methods: using a stapler or stitching by hand. The goal was to see which method leads to fewer complications like leaks or infections. Results help surgeons choose the best appro…
Phase: NA • Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 15, 2026 12:00 UTC
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New study reveals best surgical fix for burst abdomen
Knowledge-focused CompletedThis study looked at 252 adults who had surgery for a burst abdomen (when the belly incision reopens after an operation). Researchers compared two repair methods: primary repair (stitching the wound back together) and component separation (a more complex technique). The goal was …
Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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New surgical approach may cut bile duct injuries in half
Knowledge-focused CompletedThis study compared two techniques for removing the gallbladder: one that focuses on a specific artery and the back of the gallbladder, and another that focuses on a clear view of key structures. The goal was to see which method leads to fewer bile duct injuries. 300 adults havin…
Phase: NA • Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC
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Blood test may predict allergy shot success
Knowledge-focused CompletedThis study looked at whether two substances in the blood, sST2 and miR-223, can help doctors know how well a treatment called sublingual immunotherapy (SLIT) works for people with dust mite allergies. 54 people with moderate-to-severe allergies received SLIT for 6 months. The goa…
Phase: PHASE1 • Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 11, 2026 20:37 UTC
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Stump closure methods compared in 666 appendix patients
Knowledge-focused CompletedThis study looked at different methods doctors use to close the base of the appendix after removing it in people with complicated appendicitis. Researchers compared how often a leak happened with each method. The study included 666 adults aged 18 and older.
Sponsor: Zagazig University • Aim: Knowledge-focused
Last updated May 07, 2026 18:39 UTC