Xuanwu Hospital, Beijing

This study tests if a newer clot-busting drug (tenecteplase) works better than the current standard (alteplase) when given before a mechanical procedure to remove a large blood clot from the brain in people having an acute stroke. About 850 adults who arrive at the hospital withi…

This study tests whether a structured rehabilitation program can delay or prevent degeneration of the spine near the surgery site in frail adults aged 75 and older who have had short-segment lumbar fusion. About 212 participants will be randomly assigned to either the rehab progr…

This study looks at whether giving a clot-dissolving drug called tenecteplase before moving patients from one hospital to a stroke center can improve recovery after a severe stroke caused by a blockage in the basilar artery. The trial involves 316 adults who had a stroke 4.5 to 2…

This study tests a new treatment made from stem cell exosomes (tiny particles) given through an IV to people who recently had a stroke. The goal is to see if it is safe and helps improve recovery. About 29 adults aged 18-70 with moderate to severe stroke symptoms will take part. …

This study tests a drug called everolimus in 10 adults with vascular malformations (abnormal blood vessels). The goal is to see if the drug can shrink these malformations and lower the risk of bleeding. Participants take the drug by mouth and are monitored with MRI scans over a y…

This study tests whether a ketogenic diet (a high-fat, low-carb diet) can help stop super-refractory status epilepticus—a life-threatening condition where seizures continue despite strong medications. About 84 ICU patients aged 14–80 will be randomly assigned to receive the diet …

This study tests whether performing skull surgery early, before dangerous brain swelling occurs, can improve outcomes for people who have had a severe stroke. About 380 participants aged 18-75 with large strokes and high swelling risk will be randomly assigned to either early sur…

This study tests whether adding a drug called batroxobin to standard blood thinners helps people with blood clots in the brain (cerebral venous thrombosis) recover faster. About 72 adults will receive either standard care or standard care plus batroxobin. The main goal is to see …

This study tests whether using a balloon guide catheter that temporarily stops blood flow helps remove clots more effectively in people having a stroke caused by a blocked internal carotid artery. About 364 adults will be randomly assigned to receive either the balloon catheter o…

This study looks at whether giving a clot-busting drug called tenecteplase to stroke patients before they are moved to a specialized hospital can improve their recovery. About 572 adults with a large blood clot in the brain, who can be treated within 4.5 to 24 hours of symptoms s…

This early-phase study tests whether adding near-infrared light therapy to the drug lecanemab can improve thinking and memory in people with mild Alzheimer's disease. About 20 participants will receive either the light therapy or a sham device, plus lecanemab, for 16 weeks, follo…

This study aims to develop a blood test to diagnose Parkinson's disease and similar brain disorders more accurately and earlier. Researchers will use a technique called RT-QuIC to detect misfolded proteins in blood samples from about 458 participants, including healthy controls a…

This early-stage trial tests whether injecting special cell particles into the spinal fluid can safely help people with syringomyelia whose symptoms haven't improved after surgery or observation. The study involves 18 adults and focuses on safety and any signs of symptom relief.

This early-stage study tests whether galcanezumab, a drug used for migraines, can help people with mild-to-moderate Alzheimer's disease. Ten participants will receive injections every four weeks for 24 weeks. Researchers will measure changes in a brain chemical called CGRP and tr…

This pilot study tests whether everolimus, a drug that targets a specific cell pathway, can safely reduce seizures in adults with focal epilepsy that doesn't respond to standard medications. Five participants will take everolimus alongside their usual drugs for 12 weeks. The goal…

This study is testing whether a non-invasive brain stimulation technique called hi-tACS can help people with neuroimmune diseases (like multiple sclerosis) who also have trouble sleeping. Researchers will measure sleep quality before and after treatment in 80 participants. The go…

This study tests a 6-week prehabilitation program for adults aged 75 and older who need spine surgery for lower back problems. The program includes exercise, nutrition advice, health optimization, and brain exercises. Researchers want to see if it helps patients stay independent …

This study looks back at medical records of 2600 stroke patients who received clot-busting medication between 4.5 and 24 hours after their stroke started. The goal is to see how many had good recovery (able to live independently) despite the delayed treatment. It does not test a …

This study follows 500 adults who had a brain hemorrhage and received surgery. Researchers will track their recovery and quality of life over time to see which surgical approach works best. The goal is to improve future treatment decisions for this serious condition.

This study follows 1000 adults in intensive care after a brain aneurysm bursts. Researchers want to learn how often delayed brain injury occurs, how doctors diagnose it, and which treatments work best. The goal is to gather real-world data to improve future care, not to test a ne…

This study is looking at 200 people with severe narrowing in the neck arteries that supply the brain. Researchers will use a special PET/MR scanner to measure blood flow and sugar use in the brain. The goal is to find better ways to diagnose and treat patients at risk for stroke.…