Snake venom enzyme could boost stroke recovery in rare brain clot study

NCT ID NCT07352358

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding batroxobin, a snake venom enzyme that dissolves clots, to standard blood thinners helps people with acute cerebral venous thrombosis (a rare stroke caused by a clot in a brain vein). Seventy-two adults will be randomly assigned to receive either standard anticoagulation alone or anticoagulation plus batroxobin. The main goal is to see if more patients achieve complete clot clearance within 7 days with the combination therapy.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
batroxobin (a snake venom enzyme that breaks down blood clots) plus standard anticoagulants (low-molecular-weight heparin, warfarin, rivaroxaban, or dabigatran)
What this could lead to
If successful, this combination could speed up clot removal and improve recovery for people with cerebral venous thrombosis, a rare type of stroke.
What could go wrong
This is a small, early-phase 4 trial with only 72 participants, so results may not apply broadly. Batroxobin can increase bleeding risk, especially when combined with blood thinners.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Xuanwu Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100053, China

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