Snake venom enzyme could boost stroke recovery in rare brain clot study
NCT ID NCT07352358
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tests whether adding batroxobin, a snake venom enzyme that dissolves clots, to standard blood thinners helps people with acute cerebral venous thrombosis (a rare stroke caused by a clot in a brain vein). Seventy-two adults will be randomly assigned to receive either standard anticoagulation alone or anticoagulation plus batroxobin. The main goal is to see if more patients achieve complete clot clearance within 7 days with the combination therapy.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- batroxobin (a snake venom enzyme that breaks down blood clots) plus standard anticoagulants (low-molecular-weight heparin, warfarin, rivaroxaban, or dabigatran)
- What this could lead to
- If successful, this combination could speed up clot removal and improve recovery for people with cerebral venous thrombosis, a rare type of stroke.
- What could go wrong
- This is a small, early-phase 4 trial with only 72 participants, so results may not apply broadly. Batroxobin can increase bleeding risk, especially when combined with blood thinners.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Xuanwu Hospital
RECRUITINGBeijing, Beijing Municipality, 100053, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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