Could a High-Fat diet tame Super-Refractory seizures?
NCT ID NCT07496749
First seen Apr 22, 2026 · Last updated Jun 20, 2026 · Updated 10 times
Summary
This study is testing whether a ketogenic diet (a high-fat, low-carbohydrate diet) can help stop super-refractory status epilepticus—a life-threatening condition where seizures continue despite standard medications. The diet is given via feeding tube or by mouth to 84 ICU patients aged 14–80. Researchers will measure how quickly seizures stop using brain wave monitoring.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beijing Tongren Hospital, Capital Medical University
NOT_YET_RECRUITINGBeijing, 100730, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Chifeng Municipal Hospital
RECRUITINGChifeng, Neimenggu, 024000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Department of Neurology, Xuanwu Hospital Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100053, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fujian Medical University Union Hospital
RECRUITINGFuzhou, Fujian, 350001, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Guizhou Provincial People's Hospital
RECRUITINGGuiyang, Guizhou, 550002, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Liaocheng People's Hospital
RECRUITINGLiaocheng, 252000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Qilu Hospital，Shandong University
NOT_YET_RECRUITINGJinan, Shandong, 2500012, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Anhui Medical University
RECRUITINGHefei, Anhui, 230022, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Guangxi Medical University
RECRUITINGNanning, Guangxi, 530021, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Harbin Medical University
RECRUITINGHarbin, Heilongjiang, 150001, China
Contact Email: •••••@•••••
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The First Hospital of Hebei Medical University
RECRUITINGShijiazhuang, Hebei, 050031, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Hospital of Jilin University
RECRUITINGJilin City, 130021, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Affiliated Hospital of Hainan Medical University
NOT_YET_RECRUITINGHaikou, Hainan, 570311, China
Contact Email: •••••@•••••
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The Second Affiliated Hospital of Zhejiang University School of Medicine
RECRUITINGHanzhou, Zhejiang, 310009, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketogenic diet (a high-fat, low-carbohydrate diet given via feeding tube or by mouth)
What this could lead to
If it works, this could offer a new, drug-free option to stop prolonged seizures in the ICU, potentially reducing brain damage and time on life support.
What could go wrong
This is a relatively small trial (84 people) and the diet can cause side effects like digestive issues or nutrient imbalances. It may not work for everyone, and results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.