New hope for Hard-to-Stop seizures? early trial tests SAGE-547

NCT ID NCT02052739

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 40 times

Summary

This study tested a drug called SAGE-547 in 25 people aged 2 and older who were having a severe, life-threatening seizure that did not stop with standard treatments. The main goal was to see if the drug was safe and tolerable. The study was completed, but results are not yet available.

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Contacts and locations

Locations

  • Sage Investigational Site

    Birmingham, Alabama, 35294, United States

  • Sage Investigational Site

    Sarasota, Florida, 34239, United States

  • Sage Investigational Site

    Chicago, Illinois, 60611, United States

  • Sage Investigational Site

    Wichita, Kansas, 67214, United States

  • Sage Investigational Site

    New Orleans, Louisiana, 70121, United States

  • Sage Investigational Site

    Boston, Massachusetts, 02114, United States

  • Sage Investigational Site

    Boston, Massachusetts, 02115, United States

  • Sage Investigational Site

    Ann Arbor, Michigan, 48109, United States

  • Sage Investigational Site

    Detroit, Michigan, 48322, United States

  • Sage Investigational Site

    New York, New York, 10032, United States

  • Sage Investigational Site

    Rochester, New York, 14642, United States

  • Sage Investigational Site

    Durham, North Carolina, 27710, United States

  • Sage Investigational Site

    Winston-Salem, North Carolina, 27157, United States

  • Sage Investigational Site

    Philadelphia, Pennsylvania, 19104, United States

  • Sage Investigational Site

    Nashville, Tennessee, 37232, United States

  • Sage Investigational Site

    Dallas, Texas, 75251, United States

  • Sage Investigational Site

    Temple, Texas, 76504, United States

Conditions

The condition(s) this trial relates to.

Status Epilepticus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.