Can a nasal spray of stem cell 'Messages' slow Alzheimer's?
NCT ID NCT07457125
First seen Mar 11, 2026 · Last updated Jun 19, 2026 · Updated 20 times
Summary
This early-stage trial is testing whether a nasal spray containing exosomes from umbilical cord stem cells is safe and might help people with mild to moderate Alzheimer's. The study involves 33 participants and will first test different doses, then compare the best dose to a placebo. The main focus is on safety, but researchers will also check if it affects memory and thinking.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Xuanwu Hospital, Capital Medical University
RECRUITINGBeijing, 100053, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
exosomes derived from umbilical cord mesenchymal stem cells (CB-Exo-A600) given as a nasal spray
What this could lead to
If it works, this could point toward a new way to slow or manage Alzheimer's symptoms using stem cell-derived exosomes delivered through the nose.
What could go wrong
This is an early Phase 1/2 trial with only 33 participants, so it is too small to prove effectiveness. The main goal is safety, and it is unknown if the treatment will actually help memory or thinking.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.