Can a nasal spray of stem cell 'Messages' slow Alzheimer's?
NCT ID NCT07457125
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial is testing whether a nasal spray containing exosomes from umbilical cord stem cells is safe and might help people with mild to moderate Alzheimer's. The study involves 33 participants and will first test different doses, then compare the best dose to a placebo. The main focus is on safety, but researchers will also check if it affects memory and thinking.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- exosomes derived from umbilical cord mesenchymal stem cells (CB-Exo-A600) given as a nasal spray
- What this could lead to
- If it works, this could point toward a new way to slow or manage Alzheimer's symptoms using stem cell-derived exosomes delivered through the nose.
- What could go wrong
- This is an early Phase 1/2 trial with only 33 participants, so it is too small to prove effectiveness. The main goal is safety, and it is unknown if the treatment will actually help memory or thinking.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Xuanwu Hospital, Capital Medical University
RECRUITINGBeijing, 100053, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.