Could a Telomerase-Based peptide slow Alzheimer's? new trial results are in
NCT ID NCT05189210
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase 2 study tested two doses of GV1001, a synthetic peptide, against a placebo in 199 people with mild to moderate Alzheimer's. The goal was to see if the drug could improve thinking and daily function over 52 weeks. Earlier lab and animal studies suggested GV1001 might protect brain cells and reduce harmful proteins linked to Alzheimer's.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
GV1001 (a synthetic peptide derived from a protein linked to telomerase)
What this could lead to
If successful, GV1001 could offer a new treatment option to slow cognitive decline in people with mild to moderate Alzheimer's disease.
What could go wrong
This is an early-phase trial with a small number of participants. The results may not hold up in larger studies, and the drug may cause side effects or fail to show clear benefits.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Accel Research Sites (ARS) - NeuroStudies
Decatur, Georgia, 30033, United States
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Aqualane Clinical Research
Naples, Florida, 34105, United States
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Brain Research Center - Amsterdam
Amsterdam, North Holland, 1081 GN, Netherlands
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Brain Research Center - Zwolle
Zwolle, Overijssel, 8025 AZ, Netherlands
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Brain Research Centre - Den Bosch
Amsterdam, Netherlands
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Casa di Cura iGEA SpA c/o Casa di Cura Privata del Policlinico
Milan, 20144, Italy
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Centrum Medyczne Neuromed - Ośrodek Badań Klinicznych
Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-163, Poland
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Centrum Medyczne Neuroprotect
Warsaw, Masovian Voivodeship, 01-684, Poland
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Clinhouse Centrum Medyczne
Zabrze, Silesian Voivodeship, 41-807, Poland
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Finlay Medical Research Corporation - Greenacres
Greenacres City, Florida, 33467, United States
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Finlay Medical Research Corporation - Miami Dade
Miami, Florida, 33126, United States
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First Choice Neurology - Aventura Neurologic Associates
Adventura, Florida, 33180, United States
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Flourish Research - Alzheimer's Memory Center/AMC Research, LLC
Charlotte, North Carolina, 28270, United States
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Fundacio ACE
Barcelona, Spain
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Galen Clinic
Lublin, Lublin Voivodeship, 20-064, Poland
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Global Medical Institutes - Princeton Medical Institute
Princeton, New Jersey, 08540, United States
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Hospital Clinic de Barcelona
Barcelona, 08036, Spain
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Hospital Pedro Hispano
Senhora da Hora, Porto District, 4464-513, Portugal
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Hospital Universitari Vall d'Hebrón
Barcelona, 08035, Spain
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Hospital Universitari i Politècnic La Fe
Valencia, 46026, Spain
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Hospital Universitario Quirónsalud Madrid
Pozuelo de Alarcón, Madrid, 28223, Spain
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Hospital Universitario Virgen del Rocío
Seville, 41013, Spain
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Hospital Victoria Eugenia
Seville, 41009, Spain
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Hôpital La Grave
Toulouse, Midi-Pyrenees, 31300, France
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Hôpital Pierre Wertheimer
Bron, Rhône, 69677, France
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Neurology Clinic - Cordova
Cordova, Tennessee, 38018, United States
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Neurostudies - Port Charlotte
Port Charlotte, Florida, 33952, United States
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Niepubliczny Zakład Opieki Zdrowotnej NOVO-MED
Katowice, Silesian Voivodeship, 40-584, Poland
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Outpatient Psy Care
Miami, Florida, 33125, United States
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Palm Beach Neurological Center
Palm Beach Gardens, Florida, 33410, United States
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Palm Beach Neurology and Premiere Research Institute
West Palm Beach, Florida, 33407, United States
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Terveystalo Oulu
Oulu, 90100, Finland
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Unidade Local de Saúde de Braga, E. P. E (Hospital de Braga)
Braga, 4710-243, Portugal
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Unidade Local de Saúde de Santa Maria, E. P. E. - Hospital de Santa Maria
Lisbon, Lisbon District, 1649-035, Portugal
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Wroctawskie Centrum Alzheimerowskie (WCA)
Wroclaw, Lower Silesian Voivodeship, 53-659, Poland