University Of Cincinnati

This study is testing whether using real-time monitoring of harmful brain waves, called spreading depolarizations, can help doctors better guide treatment for patients with severe traumatic brain injury (TBI). About 72 patients who need emergency brain surgery will be enrolled. T…

This study is comparing two different forms of a brain nutrient called DHA to see which one is better at getting into the brain and spinal fluid of older adults who are noticing early signs of memory decline. Researchers will give 153 participants either one of the DHA supplement…

This study is testing if an experimental injection called AM3101 can help knee meniscus tears heal better after surgical repair. About 74 adults aged 18-40 with a meniscus tear will receive either the AM3101 injection or a placebo (saltwater) during their repair surgery. Research…

This study is testing if combining mindfulness-based cognitive therapy (a talk therapy) with a supplement called N-acetylcysteine (NAC) is better than either one alone for helping young people (ages 15-24) with mild depression. Researchers will use brain scans to see how these tr…

This study aims to find out if a clot-removal procedure is safe and effective for stroke patients who already had moderate-to-severe disabilities before their stroke. It will compare the procedure plus standard medical care against standard medical care alone. The goal is to dete…

This study is testing whether a simple, 8-week program of tongue-strengthening exercises done at home can improve swallowing difficulties in adults who have had a stroke. Researchers will compare the exercise program to a sham therapy to see which is better at helping people swal…

This study compares two standard methods for delivering numbing medicine to breast cancer patients having a total mastectomy. Researchers want to see which approach—giving the numbing medicine before surgery versus during surgery—better controls pain and reduces the need for opio…

This early-stage study is checking if a probiotic supplement called Pendulum Glucose Control (PGC) is safe and practical for patients to take during pelvic radiation therapy. Researchers want to see if it can help reduce common stomach and bowel side effects like diarrhea and cra…

This study aims to understand if a natural protein called C-peptide can help the liver make more sugar during episodes of low blood sugar (hypoglycemia). Researchers will compare people with type 1 diabetes to healthy volunteers to see if giving C-peptide during a controlled low …

This study aims to validate tests that can predict how well a person's arm will recover after a stroke. Researchers will use brain scans and a safe, non-invasive brain stimulation technique on about 657 recent stroke patients. The goal is to create reliable tools to identify whic…