Tiny protein may shield diabetics from low blood sugar danger
NCT ID NCT06470295
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tests whether a natural protein called C-peptide can help the liver produce more sugar during insulin-induced low blood sugar in people with type 1 diabetes. Researchers will give C-peptide or a placebo to 38 volunteers and measure glucagon levels and liver sugar production. The goal is to understand if C-peptide could one day reduce the risk of severe hypoglycemia.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
C-peptide
What this could lead to
If it works, this could point toward a new way to prevent severe low blood sugar episodes in people with type 1 diabetes.
What could go wrong
This is a very early, small study (38 people) testing a biological mechanism, not a treatment. It may not translate into a real-world therapy.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for TYPE 1 DIABETES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
University of Cincinnati
RECRUITINGCincinnati, Ohio, 45267-0547, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••