Brain scans reveal how language therapy rewires Kids' brains

NCT ID NCT05268341

First seen May 29, 2026

Summary

This study uses brain imaging to understand how a computer-based grammar program affects brain connections in preschoolers with Developmental Language Disorder (DLD). Researchers will scan children's brains before and after therapy to see changes in memory and language networks. The goal is to learn how the brain supports grammar learning, which could lead to better, more personalized treatments for DLD.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CWFF CHild Development Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cincinnati Children's Hospital

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Empower Learn Create INC

    RECRUITING

    Cincinnati, Ohio, 45220, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • New Horizon Childcare

    NOT_YET_RECRUITING

    Cincinati, Ohio, 45207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45267, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wesley Education Center for Children and Families

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

My Sentence Builder (computer-assisted treatment program for expressive grammar)

What this could lead to

If successful, this could reveal how the brain changes with grammar therapy, helping design more personalized treatments for children with language disorders.

What could go wrong

This is an early-stage observational study with no treatment outcome data yet. The brain changes seen may not translate to better language skills, and results may not apply to all children.

Conditions

The condition(s) this trial relates to.

familial developmental dysphasia Language Development Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.