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New injection aims to boost meniscus healing after surgery

NCT ID NCT05560477

Recruiting now Disease control Sponsor: University of Cincinnati Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests an injectable drug called AM3101 to see if it can improve healing of meniscus tears in the knee after surgical repair. About 74 people aged 18 to 40 with a torn meniscus will be randomly assigned to receive either AM3101 or a saline placebo during surgery. The trial is double-blinded, meaning neither patients nor doctors know who gets the real drug, and will track healing via MRI and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
AM3101 (an injectable drug)
What this could lead to
If it works, this could lead to a treatment that helps meniscus tears heal better after surgery, reducing the need for repeat procedures.
What could go wrong
This is an early phase 1/2b trial with only 74 people, so results may not apply widely. The drug could also cause side effects or not improve healing compared to placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MENISCUS TEAR

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45267, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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