Can a supplement and meditation lift mild depression in teens?
NCT ID NCT07464886
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a supplement called N-acetylcysteine (NAC) and mindfulness-based therapy can help young people aged 15 to 24 with mild depression. Participants will take NAC or a placebo and attend mindfulness or sham therapy sessions for 8 weeks. The goal is to see if these treatments improve brain chemistry and mood.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
N-acetylcysteine (NAC)
What this could lead to
If successful, this could point toward a new, non-drug treatment option for mild depression in young people.
What could go wrong
This is an early-stage trial with only 160 participants, so results may not apply to everyone. The treatment may not work better than placebo.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Cincinnati, Department of Psychiatry and Behavioral Neuroscience
RECRUITINGCincinnati, Ohio, 45219, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••