Can a supplement and meditation lift mild depression in teens?
NCT ID NCT07464886
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a supplement called N-acetylcysteine (NAC) and mindfulness-based therapy can help young people aged 15 to 24 with mild depression. Participants will take NAC or a placebo and attend mindfulness or sham therapy sessions for 8 weeks. The goal is to see if these treatments improve brain chemistry and mood.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- N-acetylcysteine (NAC)
- What this could lead to
- If successful, this could point toward a new, non-drug treatment option for mild depression in young people.
- What could go wrong
- This is an early-stage trial with only 160 participants, so results may not apply to everyone. The treatment may not work better than placebo.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Cincinnati, Department of Psychiatry and Behavioral Neuroscience
RECRUITINGCincinnati, Ohio, 45219, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.