University Hospital, Lille

This study is testing whether using a freezing treatment (cryotherapy) followed by a prescription ointment (tirbanibulin) works better than freezing alone for actinic keratosis, a common skin condition caused by sun damage. The goal is to see if this combination leads to more com…

This study aims to see if special training for family doctors can help slow the loss of kidney function in older adults with long-term type 2 diabetes. It will compare 360 patients whose doctors receive this training to a group receiving usual care. The main goal is to measure if…

This study is testing if a drug already used for multiple sclerosis (diroximel fumarate) can safely reduce dangerous brain swelling that occurs after a bleeding stroke. Researchers believe calming brain inflammation with this drug may help patients recover better. The trial will …

This study is testing whether adding one session of hyperbaric oxygen therapy to standard intensive care can help reduce brain damage in people who survive suicide attempts by hanging. Researchers will compare standard care alone to standard care plus the oxygen therapy in 50 pat…

This study is testing whether extending standard steroid treatment or adding an antioxidant drug called N-acetylcysteine can improve outcomes for people with severe alcoholic hepatitis. Researchers will enroll 477 adults with this serious liver condition to see if these approache…

This study is testing whether patients with multiple sclerosis or spinal cord injury can safely skip preventive antibiotics before receiving bladder injections for overactive bladder. Researchers want to see if avoiding these antibiotics does not lead to more urinary tract infect…

This study aims to see if performing a broad genetic test on tumors early in treatment, rather than later, helps find more personalized treatment options for people with advanced pancreatic, liver, or triple-negative breast cancer. It will compare two approaches: one group gets t…

This study aims to find out which of two less-invasive surgery methods is better for people with esophageal cancer. It will compare a 'totally' minimally invasive approach to a 'hybrid' approach in about 327 patients. The main goal is to see which method leads to fewer serious co…

This study is testing a type of PET scan called 18FET to see if it can better detect hormone-producing pituitary tumors when the standard MRI scan is unclear. It will enroll about 30 adults with these tumors, either newly suspected or returning after previous treatment. The goal …

This study is testing a new device called TOCONAUTE that monitors a baby's stress levels during labor. The goal is to see if it can better detect when a baby is not getting enough oxygen, which can lead to brain damage. Researchers will enroll 760 pregnant women to see if this ne…

This study is testing whether a new type of shoe called CHUT OTONOM® can help older adults walk more steadily and reduce their risk of falling. Researchers will compare how 94 elderly participants walk while wearing these special shoes versus their usual footwear. The goal is to …

This study compares two different pain control methods for patients recovering from minimally invasive esophageal cancer surgery. Researchers want to see if a newer method called paravertebral catheter provides similar pain relief to the current standard method while potentially …

This study aims to understand how a newer combination drug therapy (ETI) affects breathing during exercise in adults with cystic fibrosis. Researchers will observe 130 adult patients who are already taking ETI therapy, measuring their breathing during walking tests. The goal is t…

This study aims to understand why women in the Hauts-de-France region experience longer delays in breast cancer care despite similar cancer rates. Researchers will track 500 women's journeys from first symptoms to treatment, measuring time between key steps like mammograms and bi…

This study aims to create better tools for measuring how well pediatric intensive care units (ICUs) perform. It will follow over 13,000 children under 18 across 14 French hospitals to validate scoring systems that predict survival and treatment costs. The goal is to help hospital…

This study aims to find out if adding a simple summary written by artificial intelligence (AI) helps adults understand their brain MRI reports for headaches. Researchers will ask about 1200 people to read fictional MRI reports online—some with an AI summary and some without—and a…

This is a lab study using blood samples to understand how a modified clot-busting drug works in people with different bleeding risks. Researchers will create clots from donor blood and test personalized drug doses to see how well they break down the clots. The goal is to gather k…

Currently in France, screening for congenital hypothyroidism (CH) in premature infants is done by a single TSH assay on filter paper. However, European recommendations advise repeating the assay within the first month of life. Our primary objective is to estimate the incidence o…