Could skipping antibiotics before bladder botox be safe? new trial aims to find out

NCT ID NCT05534399

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether it is safe to avoid antibiotics before bladder Botox injections in people with multiple sclerosis or spinal cord injury who have bacteria in their urine but no symptoms. About 526 participants will be randomly assigned to receive either antibiotics or no antibiotics around the time of the procedure. The goal is to see if skipping antibiotics leads to more urinary tract infections in the six weeks after the injection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

antibiotic therapy (or no antibiotic therapy)

What this could lead to

If successful, this could show that many patients can safely avoid antibiotics before bladder Botox injections, reducing antibiotic overuse and side effects.

What could go wrong

This is a relatively small, early-stage trial. It may find that skipping antibiotics increases the risk of symptomatic urinary tract infections, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bacteriuria multiple sclerosis spinal cord injury urinary system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hop Claude Huriez Chu Lille

    Lille, 59037, France

    Contact Phone: •••-•••-••••