A smarter urine test? new biomarkers aim to end UTI guesswork

NCT ID NCT07766278

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This study is testing whether new biomarkers in urine can more accurately diagnose urinary tract infections (UTIs) in two groups where current tests often fail: young children not yet toilet-trained and adults aged 65 and older. In these groups, standard urine tests can be misleading—contamination in kids and harmless bacteria in older adults can lead to false positives. By analyzing leftover urine samples from routine care, researchers hope to find markers that distinguish a true infection from these confounders, potentially reducing unnecessary antibiotic use and hospital admissions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Novel urinary host and bacterial biomarkers
What this could lead to
If successful, this could lead to a more accurate urine test that reduces unnecessary antibiotics and hospital admissions for UTIs in children and older adults.
What could go wrong
This is an observational study, so it won't directly test a treatment. The biomarkers may not prove accurate enough in real-world settings, and results may not apply to all populations.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Queen's University Belfast

    Belfast, Northern Ireland, BT9 7BL, United Kingdom

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