Could viruses replace antibiotics for bladder infections in spinal cord injury?
NCT ID NCT06559618
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage study tests whether a mixture of viruses (called phages) that specifically kill E. coli bacteria is safe for people with spinal cord injuries who have bacteria in their bladder. Thirty adults will receive the phage solution directly into the bladder twice daily for a week. The main goal is to check for side effects and see how the body handles the treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bacteriophage therapy (viruses that target E. coli bacteria)
What this could lead to
If it works, this could point toward a new way to control bladder bacteria in spinal cord injury patients without using antibiotics.
What could go wrong
This is a very early (Phase 1) study with only 30 people, so it's mainly checking safety, not effectiveness. The therapy is personalized and may not work for everyone.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Michael E. DeBakey VA Medical Center
RECRUITINGHouston, Texas, 77030, United States
Contact Email: •••••@•••••
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Washington University in St Louis
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Email: •••••@•••••