Freeze then ointment: new combo tackles precancerous skin spots
NCT ID NCT07273656
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether freezing precancerous skin spots (cryotherapy) followed by a medicated ointment (tirbanibulin) works better than freezing alone for actinic keratosis on the scalp and forehead. About 59 adults with at least 8 spots will receive the combo treatment or a placebo ointment after freezing, repeated every 4 months. The main goal is to see if all spots clear up at 8 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tirbanibulin ointment
What this could lead to
If successful, this combination treatment could offer a more effective way to clear actinic keratosis lesions on the scalp and forehead, reducing the need for repeated procedures.
What could go wrong
This is a small Phase 3 trial (59 participants) and results may not apply to everyone. The treatment involves multiple cycles and side effects from cryotherapy or the ointment are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.