Laser rejuvenation may shield aging skin from cancer

NCT ID NCT03906253

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests whether a single session of fractionated laser resurfacing on one forearm can reduce precancerous spots (actinic keratosis) and prevent future non-melanoma skin cancers in older adults with fair skin. Participants are at least 60 years old and have had actinic keratosis in the past six months. The treated arm is compared to the untreated arm over five years of follow-up.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Fractionated laser resurfacing (FLR) — a device that creates tiny holes in the top layer of skin to rejuvenate it.
What this could lead to
If successful, this approach could offer a one-time treatment to lower the risk of precancerous spots and skin cancer in older adults.
What could go wrong
This is a small, early-stage study with only 72 participants, and results may not apply to everyone. The laser treatment may cause temporary redness or scarring.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dayton VA Medical Center

    RECRUITING

    Dayton, Ohio, 45428, United States

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