University Hospital, Lille

This study tested whether a special antibody treatment (Cytotect®CP) could safely prevent dangerous cytomegalovirus (CMV) infections in patients who had received a stem cell transplant and developed graft-versus-host disease (GVHD). The trial focused on patients at very high risk…

This study tested a decision-making tool to identify children with cancer who have a low risk of severe infection when they develop fever and low white blood cell counts (febrile neutropenia). The goal was to see if using this rule could safely allow more children to be treated a…

This study aimed to see if adding surgery to remove the main stomach tumor and a single metastatic site to standard chemotherapy helps patients with a limited spread of stomach cancer live longer and feel better than chemotherapy alone. It was a large, randomized Phase 3 trial, b…

This small, early-stage study aimed to see if a new long-acting inhaler (PT003) could improve the irregular and complex breathing patterns in people with stable, moderate-to-severe COPD. Only four participants were enrolled to measure changes in breathing mechanics and lung funct…

This study monitored 239 patients in France who were prescribed baclofen for alcohol use disorder. Researchers conducted monthly phone calls for one year to track side effects and determine how often patients stopped the medication due to adverse events. The goal was to better un…

This study tested if a drug called eltrombopag could help patients whose blood cell counts remained dangerously low after a stem cell transplant for leukemia, a condition known as poor graft function. The goal was to see if the drug could boost platelet, red blood cell, and white…

This study aimed to see if giving antibiotics to critically ill patients on breathing machines who develop a specific lung infection (ventilator-associated tracheobronchitis) could prevent it from turning into a more serious pneumonia. It compared giving no antibiotics to giving …

This study tested whether using ultrasound could improve how doctors diagnose ankle injuries in children. Researchers compared ultrasound results to MRI scans (considered the most accurate method) in 97 children with ankle injuries. The goal was to see if ultrasound could help do…

This study aimed to compare two tools used to collect cells from inside the cervix during a diagnostic procedure. It tested whether a brush-like tool (cytobrush) causes less pain than the standard scraping tool (Kevorkian curette) while still collecting enough cells for accurate …

This study aimed to see if a breathing and exercise program done at home is as effective as the same program done at a medical center for people with COPD. It involved 188 adults with moderate to severe COPD and measured their exercise ability, breathlessness, and quality of life…

This study aimed to understand how a light-based blood treatment called extracorporeal photopheresis (ECP) works in patients with chronic graft-versus-host disease (cGVHD). Researchers followed 8 patients receiving ECP along with standard steroid medications to see how the treatm…

This study aimed to understand how healthy brothers and sisters of children with blood cancer receive information about their sibling's illness. Researchers interviewed 7 siblings aged 6-12 to learn about their satisfaction with how they were told, what they understood about the …

This study aimed to create detailed 3D maps of the pelvic cavity to help doctors personalize treatments for pelvic floor disorders. Researchers used a special MRI scan along with a small pressure probe to measure tissue characteristics in women who needed a pelvic MRI. The goal w…