University Hospital, Lille

This study aimed to see if feeding through a tube into the gut (enteral nutrition) helps heal leaks after upper digestive surgery better than feeding through a vein (parenteral nutrition). It included adults who had a leak after surgery on the esophagus, stomach, duodenum, pancre…

This study tested the drug eltrombopag in 9 people who had poor graft function after a stem cell transplant for leukemia. Poor graft function means the new donor cells don't make enough blood cells, leading to low platelets and other issues. The goal was to see if eltrombopag cou…

This study looked at whether giving antibiotics to ICU patients with a lung infection called ventilator-associated tracheobronchitis (VAT) could stop it from turning into pneumonia. About 103 adults on breathing machines took part. The trial was stopped early, so the results are …

This study looked at whether removing the main stomach tumor and treating the single spot where cancer had spread, along with chemotherapy, helps people with stage IV stomach cancer live longer. It was designed for patients whose cancer had not worsened after initial chemo. The t…

This study tested whether regular phone calls from a healthcare team could help people with anorexia nervosa maintain a healthy weight after their first hospital stay. The study planned to include people aged 15 and older, but was stopped early with only 19 participants. The goal…

This study looked at whether doing breathing exercises at home works as well as doing them at a clinic for people with chronic obstructive pulmonary disease (COPD). The trial involved 188 adults with moderate to severe COPD. Researchers measured exercise ability, breathing diffic…

This study tested a medicine called Cytotect to prevent cytomegalovirus (CMV) infection in people who had a stem cell transplant and then developed graft-versus-host disease (GVHD). CMV is a common virus that can be very dangerous for these patients. The goal was to see if Cytote…

This study looked at whether ultrasound can accurately diagnose ankle injuries in children, compared to the gold standard MRI. It involved 97 children aged 5 to 17 with ankle trauma. The goal was to see if ultrasound could be a faster, simpler tool for diagnosis, but the study wa…

This study tested a special multi-line device (Edelvaiss Multiline NEO) to see if it could prevent bloodstream infections caused by catheters in very premature infants. The device was compared to standard infusion sets in 87 babies born between 24 and 29 weeks. The study was term…

This study tested a special ankle brace called CALIGALOC to see if it helps people with leg weakness (hemiparesis) and ankle turning (varus) walk better. Only 5 people took part, and the study was stopped early. The brace was meant to improve walking speed and balance, but result…

This study looked at how healthy brothers and sisters, ages 6 to 12, experienced learning about a sibling's blood cancer. Researchers interviewed 7 children to understand their satisfaction with the information they received and how they viewed the disease. The goal was to improv…

This study looked at how adults exposed to alcohol before birth process emotions and make decisions. Researchers compared their ability to read facial expressions and control impulses to people without that exposure. The goal was to understand, not treat, these differences.

This study aimed to understand how fungal infections, especially Candida, affect people with autoimmune polyendocrinopathy (APECED). Researchers planned to compare fungal strains in patients with different types of the disease. The study was terminated early and enrolled only 7 p…

This study aimed to understand the emotional and social effects on parents who decided palliative care for their newborn. Researchers planned to interview parents and assess children's development, but only one person joined before the study was stopped. The results are very limi…

This study aimed to find biological markers (biomarkers) that could help doctors diagnose bradykinin angioedema and predict how severe attacks might be. Researchers planned to compare proteins in the blood of people with the condition against healthy controls. However, the study …

This study looked at adults with phenylketonuria (PKU) who were diagnosed as newborns and followed a special diet during childhood. The goal was to see how long they stayed on the diet and how well their phenylalanine levels were controlled affected their intelligence as adults. …

This study aimed to understand why people with COPD often get bacterial lung infections. Researchers measured immune proteins called IL-17 and IL-22 in 23 hospitalized patients during a flare-up and when stable. The goal was to see if a weak immune response to bacteria leads to r…

This early-phase study aimed to see if taking memantine, an Alzheimer's drug, for 15 days would change results on a battery of cognitive tests, brain scans, and EEGs in healthy young men aged 18-30. The goal was to validate these tests as tools for future Alzheimer's drug develop…

This study tested a clinical decision rule to help doctors identify children with cancer who have a low risk of severe infection when they develop a fever with low white blood cell counts (febrile neutropenia). The goal was to see if using this rule could safely allow some childr…

This study looked at how extracorporeal photopheresis (ECP) — a treatment that uses light to modify a patient's own blood cells — affects the immune system in people with chronic graft-versus-host disease (cGVHD), a complication after a stem cell transplant. Researchers planned t…

This study followed 239 adults in France who were starting baclofen for alcohol use disorder. Researchers called participants monthly for a year to track side effects and see how many stopped the drug because of them. The goal was to better understand the real-world safety of bac…

This study tested whether a single session of magnetic brain stimulation (called rTMS) could improve pointing movements in the affected arm of stroke survivors. The plan was to compare real stimulation to a fake (sham) session in a small group of people. However, only one person …

This study aimed to compare two methods for collecting tissue from the cervix (endocervical curettage) in women with abnormal Pap smears or positive HPV tests. The goal was to see if using a soft brush (cytobrush) causes less pain than the standard metal tool (Kevorkian curette),…

This study aimed to see if orthognathic (jaw) surgery improves quality of life for people with cleft lip and palate. Researchers planned to compare questionnaire scores before and 6 months after surgery in about 10 participants. The study was terminated early, so results are limi…

This study looked at how a part of the brain called the posterior parietal cortex helps process sensory information to control movement. Researchers tested 20 healthy, right-handed adults using brain stimulation and MRI. The goal was to understand how this region influences the m…

This study looked at how a new long-acting inhaler (PT003) affects breathing patterns in people with stable moderate-to-severe COPD. Four participants took the inhaler and had their breathing measured before, 2 hours after the first dose, and after 4 weeks of daily use. The goal …

This study aimed to create personalized 3D models of the pelvic cavity in women with pelvic floor disorders (like prolapse) using MRI and a small vaginal pressure probe. Only one participant was enrolled before the study was stopped. The goal was to better understand individual t…