University Hospital, Lille

This study tests a 4-week prehabilitation program combining exercise, nutritional supplements, and psychological support for patients with sarcopenia (muscle loss) who are about to have pancreatic cancer surgery. The goal is to see if this program reduces serious complications li…

This study looked at whether taking probiotic tablets (Lactobacillus reuteri) twice a day, along with regular tooth brushing, could reduce gum inflammation in teenagers with braces. Only 3 participants were enrolled before the study was terminated early, so no meaningful results …

This study compared two ways of feeding patients who developed a leak (fistula) after upper gastrointestinal surgery: feeding through a tube into the gut (enteral nutrition) versus feeding through a vein (parenteral nutrition). The goal was to see if enteral nutrition could help …

This study tested whether regular phone calls after a first hospital stay for anorexia nervosa could help patients maintain a healthy weight and avoid relapse. Researchers planned to compare phone-based support to standard follow-up care in people over 15. The study was terminate…

This study tested whether adding surgery to chemotherapy helps people with stage IV stomach cancer that has spread to only one other area. The goal was to see if surgery could improve survival and quality of life. However, the trial was stopped early after enrolling only 6 partic…

This study looked at whether giving antibiotics to ICU patients with a lung infection caused by a breathing tube (ventilator-associated tracheobronchitis) could stop it from turning into pneumonia. About 100 critically ill adults on ventilators took part. The trial was stopped ea…

This study tested the drug eltrombopag in 9 people whose bone marrow did not recover well after a stem cell transplant for leukemia. The goal was to see if the drug could increase platelet counts and reduce the need for transfusions. The study was stopped early, so results are li…

This study tested a drug called Cytotect, which contains antibodies against the CMV virus, to prevent CMV infection in people who had a stem cell transplant and developed graft-versus-host disease (GVHD). These patients are at high risk for CMV, and current antiviral drugs often …

This study tested a new tool called the GERONTOPOLE scale to help general practitioners identify frailty in independent adults over 65 during regular clinic visits. The goal was to see if the scale could accurately detect frailty compared to a standard geriatric assessment. The t…

This study looked at whether ultrasound can accurately diagnose ankle injuries in children aged 5 to 17. Researchers compared ultrasound results to MRI, which is considered the gold standard. The goal was to see if ultrasound could be a faster, radiation-free way to diagnose inju…

This study tested a special multi-line device (Edelvaiss Multiline NEO) to see if it could prevent bloodstream infections in very premature infants (24-29 weeks) who need IV medications and nutrition. The device was compared to standard infusion sets. Unfortunately, the trial was…

This study tested a brace called CALIGALOC designed to correct foot drop (ankle varus) in people with hemiparesis after a stroke or other brain injury. The goal was to see if wearing the brace for 15 days improved walking speed and balance. Only 5 people took part, and the study …

This phase 2 pilot study tested a new dual bronchodilator inhaler called PT003 in 4 people with stable moderate-to-severe COPD. Researchers measured breathing patterns and lung function right after the first dose and again after 4 weeks of treatment. The goal was to see if PT003 …

This study compared two devices used to collect tissue from the cervix during screening for cervical cancer: the standard Kevorkian curette and a softer cytobrush. The goal was to see if the cytobrush causes less pain while still getting enough cells for diagnosis. Only 3 women w…

This study looked at whether doing breathing and exercise training at home works as well as doing it at a rehab center for people with chronic obstructive pulmonary disease (COPD). The goal was to see if home rehab could improve exercise tolerance just as much, while also being c…

This study tested a clinical decision rule to identify children with cancer who have a low risk of severe infection when they develop a fever with low white blood cell counts (febrile neutropenia). The goal was to see if using this rule could safely allow for shorter hospital sta…

This study aimed to compare the types of Candida yeast found in patients with two forms of autoimmune polyendocrinopathy, a rare condition where the immune system attacks multiple glands. Researchers planned to collect samples from the mouth and urine of 7 participants to see how…

This study aimed to understand how oxygen delivery changes during heart surgery when a heart-lung machine is used. Researchers wanted to create a computer model to help doctors personalize oxygen levels for each patient, potentially reducing complications like kidney injury. Only…

This study aimed to understand the emotional and social effects on parents after choosing palliative care for their newborn. Researchers planned to interview parents and assess the child's development if they survived. Only one person enrolled before the study was stopped, so res…

This study tested a French version of a questionnaire that measures how much patients know about lithium, a drug used for bipolar and schizoaffective disorders. Researchers wanted to see if higher knowledge scores matched safe lithium levels in the blood. The study included 22 ho…

This pilot study measured brain activity (EEG) in 6 healthy volunteers while they performed computer tasks that test attention and memory. The goal was to develop better ways to measure thinking skills that could be used in future Alzheimer's drug trials. The study was terminated…

This study looked at whether lowering oxygen levels (hypoxia) can temporarily cause thinking problems similar to Alzheimer's disease in healthy volunteers. The goal was to create a safe, reversible test to help researchers evaluate new Alzheimer's drugs more quickly. Only 6 healt…

This study looks at adults with phenylketonuria (PKU) who were diagnosed as newborns and treated with a special diet. Researchers want to see if how long and how strictly they followed the diet as children affects their intelligence (IQ) as adults. The goal is to use this informa…

This study looked at people with cone disorders, a type of inherited eye disease that affects color vision and sharp sight. Researchers analyzed genetic changes of unknown significance to see if they cause disease. The goal was to improve genetic diagnosis, not to test a treatmen…

This study looked at how stroke changes the brain's ability to recognize emotions like fear and happiness. Researchers used MRI and EEG to compare stroke patients with healthy volunteers. The study was stopped early and only included 2 participants, so findings are very limited.

This study looked at whether sleep disorders like insomnia and nightmares are connected to suicide attempts. Researchers compared people who had just attempted suicide with those who had suicidal thoughts but no attempt. The goal was to see if sleep problems might be a trigger. T…

This study looked at how being exposed to alcohol before birth might affect adults' ability to read emotions and make decisions. Researchers planned to compare adults with prenatal alcohol exposure to those without, using computer tasks. The study was terminated early and only en…

This study looked at whether a weak immune response to bacteria in COPD patients leads to more lung infections and flare-ups. Researchers collected sputum, blood, and nasal swabs from 23 hospitalized COPD patients during a flare-up and again 8 to 16 weeks later. The goal was to m…

This study aimed to see if orthognathic (jaw) surgery improves quality of life for people born with cleft lip and palate. Researchers planned to compare questionnaire scores before and 6 months after surgery in about 10 participants. The study was terminated early, so results are…

This study tested whether a single session of magnetic brain stimulation (called rTMS) over a specific brain area could improve pointing movements in people who had a stroke. Only one person took part, and the study was stopped early. The goal was to see if the stimulation could …

This early-stage study aimed to see if taking memantine, an Alzheimer's drug, for 15 days would change certain brain and cognitive markers in healthy young men aged 18-30. The goal was to validate a test battery for future Alzheimer's drug development. However, the study was term…

This study aimed to find biomarkers (measurable substances in the blood) that could help doctors diagnose bradykinin angioedema and predict how severe attacks might be. The condition causes sudden, unpredictable swelling, and current tests don't work well for all types. Researche…

This study looked at how a part of the brain called the posterior parietal cortex helps process sensory information to control movement. Researchers tested 20 healthy, right-handed adults using brain stimulation and MRI. The goal was to understand basic brain function, not to tre…

This study looked at how extracorporeal photopheresis (ECP) — a treatment that uses light to modify a patient's own blood cells — affects the immune system in people with chronic graft-versus-host disease (cGVHD), a complication after a stem cell transplant. Only 8 people were en…

This study tracked 239 adults in France taking baclofen for alcohol use disorder. Researchers called participants monthly for a year to see how many stopped the drug due to side effects. The goal was to better understand which side effects are caused by baclofen versus other fact…

This study looked at how healthy brothers and sisters of children with blood cancer felt about the information they got about the disease. Researchers interviewed 7 children aged 6 to 12 to understand their satisfaction and what they thought about the illness. The goal was to imp…

This study tested a new way to map the pelvic cavity in women using MRI and a special vaginal pressure probe. The goal was to better understand each woman's pelvic tissue characteristics so treatments like surgery or rehabilitation could be personalized. Only one participant was …