Thomas Jefferson University

This study looks at whether eating fewer calories during a precise type of radiation therapy (SABR) can help shrink breast tumors more than radiation alone. About 80 people with early-stage breast cancer will be randomly assigned to either receive SABR with or without a calorie-r…

This study tests a drug called tebentafusp-tebn combined with procedures that treat liver tumors directly (like blocking blood flow or injecting chemotherapy) in people with a type of eye cancer that has spread to the liver. The goal is to see if the combination is safe and helps…

This early-phase study is testing two different drug combinations for people whose acute myeloid leukemia (AML) has come back or not responded to prior treatment. In one part, patients receive tazemetostat plus standard chemotherapy (CPX-351); in the other, they get palbociclib b…

This study is testing a new way to detect prostate cancer by looking at cells in a urine sample. Researchers use special imaging to find cancer-related markers on those cells. The goal is to see if this simple, non-invasive test can accurately identify prostate cancer and tell ho…

This study explores whether women can accurately collect their own samples to test for HPV, a virus that can cause cervical cancer. Researchers will compare self-collected samples with standard Pap smears in 120 women, mostly from underserved minority groups. If successful, this …

This study looks at the best way to schedule common pain relievers (acetaminophen and NSAIDs) after a cesarean delivery. About 825 women who have a C-section will be randomly assigned to take the medicines at the same time or at different times. The goal is to see which schedule …

This study tests whether a self-help smartphone toolkit based on Acceptance and Commitment Therapy can reduce anxiety and depression in adults with cystic fibrosis. About 60 participants will use the toolkit on their phones and report changes in mood and psychological flexibility…

This study looks at how social factors like stress and support might be linked to inflammation in women newly diagnosed with breast cancer. About 200 participants will fill out questionnaires and give one blood sample. The goal is to understand these connections, not to test a tr…

This study is for adults in cardiogenic shock who need a temporary heart pump called an intra-aortic balloon pump. Researchers want to see if the stiffness of a person's arteries affects how well the pump works. They will measure blood flow and other vital signs before and after …

This study aims to find the genetic causes of nonimmune hydrops fetalis, a serious condition where fluid builds up abnormally in a fetus or newborn. Researchers will use whole exome and whole genome sequencing on samples from 55 families when standard tests are negative. The goal…

This study tests whether contrast-enhanced ultrasound (CEUS) can better detect if liver cancer (HCC) has been killed by a targeted radiation treatment called TARE. Standard CT/MRI scans often take months to give a clear answer, delaying next steps. Researchers will enroll 30 pati…

This study looks at why cancer patients who have needs like help with food, housing, or transportation choose not to accept support services. Researchers will survey 500 adult cancer patients and interview a smaller group to understand their reasons. The goal is to improve how ho…