Could radiation ease severe armpit skin disease?

NCT ID NCT07414550

Recruiting now Disease control Sponsor: Thomas Jefferson University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether high-dose radiotherapy can improve symptoms of hidradenitis suppurativa, a painful skin condition. Ten adults with moderate to severe disease will receive radiation to one armpit while the other armpit gets standard care. Researchers will compare changes in inflammatory nodules, abscesses, and quality of life between the treated and untreated sides.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiation therapy
What this could lead to: If it works, this could offer a new treatment option for people with severe hidradenitis suppurativa that hasn't responded to other therapies.
What could go wrong: This is a very small early study with only 10 people, so results may not apply to everyone. Radiotherapy also carries risks like skin irritation and long-term side effects.

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Conditions

The condition(s) this trial relates to.

hidradenitis suppurativa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIDRADENITIS SUPPURATIVA (HS)

Contacts and locations

Locations

Jefferson Cherry Hill - Radiation Oncology
RECRUITING

Cherry Hill, New Jersey, 08003, United States
Thomas Jefferson University
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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