Can brain scans reveal the hidden toll of hidradenitis suppurativa?
NCT ID NCT07755670
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This observational study uses brain imaging to explore whether people with hidradenitis suppurativa (HS) have differences in resting brain activity compared to healthy individuals. Researchers will also track how these brain patterns relate to disease severity, pain, sleep, mood, and quality of life, and whether they change after routine biologic or small-molecule treatment. Adults aged 18 to 45 with HS will undergo fMRI scans, skin ultrasounds, and questionnaires, with follow-up over three months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Routine biologic or small-molecule therapy for hidradenitis suppurativa, prescribed as part of standard care
- What this could lead to
- If brain activity patterns are linked to HS symptoms, this could point toward new ways to monitor or treat the condition, possibly improving pain and quality of life.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. Results may not lead to new treatments, and brain imaging changes may not clearly relate to symptoms.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Second Xiangya Hospital of Central South University
RECRUITINGChangsha, Hunan, 410011, China
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Other studies related to the condition(s) this trial covers.
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