Thomas Jefferson University

This study tested a treatment for uveal melanoma that has spread to the liver. Tiny radioactive beads were injected into the liver's blood vessels to deliver radiation directly to tumors. The goal was to shrink or control the liver tumors. 48 patients took part, and the study loo…

This study tested whether providing medically tailored meals and nutrition counseling via telehealth can improve blood sugar control in adults with poorly controlled type 2 diabetes. About 600 participants received either usual care, tailored meals alone, or meals plus telehealth…

This study tested a special vacuum dressing called Prevena on groin wounds after vascular surgery. The goal was to see if it lowers the chance of wound problems like infection, reopening, or fluid buildup in high-risk patients. 140 adults having groin incisions for vascular repai…

This study tested a special smoking cessation program called ETIP in 19 patients with head and neck or lung cancer. The program included counseling, medication, and nicotine replacement to help patients cut down or quit smoking. Researchers also checked if reducing smoking change…

This study tested a special vacuum dressing called PREVENA on 272 adults who had a leg amputated. The goal was to see if it could lower the chance of wound problems like infection, fluid buildup, or skin reopening. Participants were randomly assigned to get either the PREVENA dre…

This study tested a three-drug combination (navitoclax, venetoclax, and decitabine) in 6 adults with high-risk myelodysplastic syndrome (MDS) that came back or didn't respond to standard therapy. The goal was to find the safest dose and see if the combo could shrink or control th…

This study tested a new way to make radiation therapy more effective for people with liver cancer. Doctors used special ultrasound contrast agents (tiny gas-filled microbubbles) and then 'popped' them with ultrasound waves to make tumors more sensitive to radiation. The study inv…

This study looked at whether a special ultrasound using gas microbubbles can predict how well bile duct cancer responds to targeted radiotherapy. The ultrasound can also pop these bubbles, which might make the cancer easier to treat. Sixteen adults with bile duct cancer took part…

This study tested a new, noninvasive ultrasound technique called SHAPE to measure pressure inside the skull. Nineteen adults who were already scheduled for a lumbar puncture (spinal tap) had their eye artery scanned with ultrasound after receiving a contrast agent. The goal was t…

This study looked at whether an automated breast ultrasound (ABUS) can be used instead of a handheld ultrasound (HHUS) to screen for breast cancer in women who have had breast reconstruction after a mastectomy. Twelve women who had nipple-sparing or skin-sparing mastectomy with r…

This study looked at how aspirin works in pregnant women at high risk for preeclampsia, a serious condition involving high blood pressure. Researchers measured platelet function and other factors in 130 women to understand why some still develop the condition despite taking aspir…

This study tested two forms of progesterone—vaginal gel and intramuscular shots—to see which better prevents another early birth in women who have already had a preterm baby. 210 pregnant women with a prior preterm birth took part. The goal was to find if the vaginal form is more…

This study looked at whether people with multiple myeloma can receive their daratumumab (Darzalex Faspro) injections at home instead of at a cancer center. Twenty adults who were already on a monthly daratumumab regimen took part. The main goal was to see if home treatment made p…

This study tested a personalized home exercise program for women with metastatic breast cancer who were not very active. The program was designed by a cancer exercise specialist to fit each patient's needs and abilities. The goal was to see if it could help them become more physi…

This small study tested whether a mindfulness program could help prevent the mental fog known as chemo brain in women about to start chemotherapy for breast cancer. Fifteen women participated, and the goal was to see if they would attend at least 6 out of 8 mindfulness sessions. …

This study looked at whether nutritional supplements, specifically N-acetyl cysteine (NAC) given orally and intravenously, could support brain function in people with Parkinson's disease. The researchers measured dopamine activity and markers of inflammation in the brain using sp…

This small study tested a 3-month program combining nightly fasting with text-based health coaching for 40 men with prostate cancer on hormone therapy. The program was found to be feasible and well-liked, with some improvements in weight and quality of life. However, the results …

This study looked at leftover tumor tissue and blood samples from 141 adults with glioblastoma or other solid tumors who were having surgery. The goal was to measure cell counts and viability to help scientists design better treatments for brain cancer and other solid tumors in t…

This completed study from Thomas Jefferson University involved 20 adults with thyroid eye disease and their caregivers. Researchers conducted focus groups and interviews to understand how the condition affects mood, relationships, work, and daily life. Participants also completed…

This study followed 105 pregnant women diagnosed with COVID-19 to learn how their immune systems responded and whether that protection passed to their babies. Researchers measured antibodies in the mothers' blood and breast milk, as well as in umbilical cord blood at delivery. Th…

This study tested a group-based well child care program for mothers receiving treatment for opioid use disorder and their infants. The goal was to see if group care, compared to individual care, could improve how often families attend checkups, parenting knowledge, and mother-chi…

This study tested whether using telehealth (video chats with doctors) and smart pill bottles can help breast cancer patients take their hormone-blocking pills more regularly. 305 people with early-stage breast cancer took part. The goal was to see if these tools improve how well …

This study looked at 67 adults who had one of three types of aortic valve replacement. Researchers used a special 3D ultrasound to measure how well the right side of the heart was pumping before and after surgery. The goal was to see if this imaging method could better detect cha…

This study looked at whether a peer-based health education program could help African American men understand prostate cancer genetic screening better. About 149 men with or without a personal or family history of prostate cancer took part. The goal was to see if talking with a t…

This study looked at 78 adults who had heart surgery and needed a breathing tube afterward. Researchers compared using a manual bag versus a mechanical ventilator to keep patients breathing during the short trip from the operating room to the intensive care unit. They measured ch…

This study looked at how factors like chronic stress and depression might speed up liver damage in Korean Americans with long-term hepatitis B infection. Researchers followed 365 participants over time, collecting health records and checking liver function. The goal was to unders…

This study looked at the safety of a newer type of nerve block called the erector spinae plane (ESP) block for people having chest surgery. Researchers measured the amount of the numbing medicine ropivacaine in the blood of 20 patients to see if it could reach dangerous levels. T…

This study looked at how COVID-19 vaccination during pregnancy or breastfeeding impacts immunity in both mothers and their infants. Researchers measured antibody levels and virus-fighting ability in blood, breastmilk, and baby saliva over time. The goal was to understand how well…

This study tested a mobile-friendly tool that helps men with prostate cancer learn about genetic testing. The tool includes educational modules and a way to collect family history. The goal was to see if the tool helps patients and doctors make better decisions about genetic test…

This early-phase study tested whether contrast-enhanced ultrasound can estimate fluid pressure inside breast tumors without needles. 25 women scheduled for breast biopsy participated. The goal was to see if the ultrasound method matches direct pressure measurements, potentially o…