New hope for tough MDS: drug trio targets resistant cancer cells
NCT ID NCT05564650
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a three-drug combination (navitoclax, venetoclax, and decitabine) in 6 adults with high-risk myelodysplastic syndrome (MDS) that came back or didn't respond to standard therapy. The goal was to find the safest dose and see if the combo could shrink or control the cancer. While not a cure, the approach aims to improve outcomes for people with limited options.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sidney Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, Pennsylvania, 19107, United States
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