New study checks safety of common painkiller in chest surgery nerve block

NCT ID NCT04807504

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at how the body processes ropivacaine, a numbing medicine, when given as a nerve block for chest surgery. Twenty adults having robotic or video-assisted chest surgery received the block, and researchers measured drug levels in their blood to check for toxicity. The goal was to better understand the safety of this newer nerve block technique.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ropivacaine (Naropin)

What this could lead to

If successful, this study could help doctors use ropivacaine more safely for nerve blocks in chest surgery, reducing the risk of serious side effects.

What could go wrong

This is a small, early-stage safety study with only 20 participants. It is not designed to prove the block works better than others, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

local anesthetic poisoning Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, 19107, United States